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  • © 2019

Evolutionary Concepts in Immunology

  • Supplements existing textbooks on immunology by providing an evolutionary perspective on the subject

  • Unifies and explains the diversity of the immune system by placing it in its evolutionary context

  • Helps students to fit their own area of interest into context with this complex field

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eBook USD 59.99
Price excludes VAT (USA)
  • ISBN: 978-3-030-18667-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 74.99
Price excludes VAT (USA)
Hardcover Book USD 109.99
Price excludes VAT (USA)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-xvi
  2. What Makes Evolution Tick?

    • Robert Jack, Louis Du Pasquier
    Pages 1-16
  3. From Unicellular to Metazoan Immunity

    • Robert Jack, Louis Du Pasquier
    Pages 17-32
  4. Innate Immunity

    • Robert Jack, Louis Du Pasquier
    Pages 33-69
  5. The Other Side of the Arms Race

    • Robert Jack, Louis Du Pasquier
    Pages 119-130
  6. Postface

    • Robert Jack, Louis Du Pasquier
    Pages 131-132
  7. Back Matter

    Pages 133-145

About this book

Immunology is a nodal subject that links many areas of biology. It permeates the biosciences, and also plays crucial roles in diagnosis and therapy in areas of clinical medicine ranging from the control of infectious and autoimmune diseases to tumour therapy. Monoclonal antibodies and small molecule modulators of immunity are major factors in the pharmaceutical industry and now constitute a multi billion dollar business. Students in these diverse areas are frequently daunted by the complexity of immunology and the astonishing array of unusual mechanisms that go to make it up.

Starting from Dobzhansky’s famous slogan, “Nothing in biology makes sense except in the light of evolution”, this book will serve to illuminate how evolutionary forces shaped immunity and thus provide an explanation for how many of its counter intuitive oddities arose. By doing so it will provide a conceptual framework on which students may organise the rapidly growing flood of immunological knowledge.

Keywords

  • Evolution
  • Immune System
  • Innate and Adaptive System Repertoires
  • Modulating Immunity in Health and Disease
  • Complex Systems

Authors and Affiliations

  • Department of Immunology, University of Greifswald, Greifswald, Germany

    Robert Jack

  • Department of Environmental Sciences, Zoology, University of Basel, Basel Stadt, Switzerland

    Louis Du Pasquier

About the authors

Prof. Jack has been trained as an immunologist in Prof Klaus Rajewsky´s lab in Cologne, and worked in developmental biology at Prof. Walter Gehring´s lab in Basel; subsequently, he has been Professor for Immunology for many years at the University of Greifswald. For more than 10 years, he has been active in the organizing committee of the Spring School for Immunology of the Deutsche Gesellschaft für Immunologie. Though retired meanwhile, he still gives introductory lectures at the Spring and Autumn School, and a lecture on Concepts in Immunology at Uni Greifswald.

Bibliographic Information

Buying options

eBook USD 59.99
Price excludes VAT (USA)
  • ISBN: 978-3-030-18667-8
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 74.99
Price excludes VAT (USA)
Hardcover Book USD 109.99
Price excludes VAT (USA)