Overview
Provides a comprehensive compendium on coronary circulation that addresses coronary circulation both globally as it relates to blood perfusion of the heart muscle, as well as locally at the site of CAD initiation and progression
Covers quantitative physiology of coronary circulation, using biomechanics to couple structure with function
Includes a detailed biomechanical synthesis of coronary circulation based on a distributive analysis of measured properties of the system (anatomy, mechanical properties, and boundary conditions)
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Table of contents (8 chapters)
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Front Matter
Keywords
- coronary Boundary Value Problems
- Morphometry of Coronary Vasculature
- Coronary Circulation Anatomy
- Coronary Circulation mechanics
- Coronary Circulation biomechanics
- 3D Coronary Vasculature
- Microstructure Coronary Vasculature
- Constitutive Models Coronary Vasculature
- Constitutive Models Coronary Vasculature
- Coronary Steady State Flow
- Network Analysis Coronary Circulation
- Coronary Pulsatile Flow
- Scaling Laws Coronary Vasculature
- Coronary Flow Stress Distribution
About this book
This comprehensive text examines both global and local coronary blood flow based on morphometry and mechanical properties of the coronary vasculature. Using a biomechanical approach, this book addresses coronary circulation in a quantitative manner based on models rooted in experimental data that account for the various physical determinants of coronary blood flow including myocardial-vessel interactions and various mechanisms of autoregulation. This is the first text dedicated to a distributive analysis (as opposed to lumped) and provides digital files for detailed anatomical data (e.g., diameters, lengths, node-to-node connections) of the coronary vessels. This book also provides appendices with specific mathematical formulations for the biomechanical analyses and models in the text. Written by Dr. Ghassan S. Kassab, a leader in the field of coronary biomechanics, Coronary Circulation: Anatomy, Mechanical Properties, and Biomechanics is a synthesis of seminal topics in the field and is intended for clinicians, bioengineers, and researchers as a compendium on the topic. The detailed anatomical and mechanical data provided are intended to be used as a platform to address new questions in this exciting and clinically very important research area.
Authors and Affiliations
About the author
Dr. Kassab received his BS (Chemical Engineering), MS (Engineering Sciences), and PhD (Bioengineering, Summa Cum Laude) from UCSD. He previously served as the Guidant Chair and Professor at Indiana/Purdue University. He is the founder and current President of California Medical Innovations Institute in San Diego.Dr. Kassab is the recipient of the NIH Young Investigator Award, AHA Established Investigator Award, Farriborz Maseeh Best Research Award, Abraham M. Max Distinguished Professor Award, Eminent Engineer Award of Tau Beta Pi Engineering Honor Society, Indiana’s President Circle Award, and Glenn IrwinChancellor Best Research Scholar Award. Dr. Kassab has published over 300full-length publications and his scientific interests encompass the biomechanics of cardiovascular and gastroenterology systems in health and disease. He also has over 250 issued or pending patents in the areas of diagnosis and treatment of heart disease, aneurysm, and obesity. Dr. Kassab’s intellectual properties have resulted in multiple start-ups and licensesto the medical device industry.
Bibliographic Information
Book Title: Coronary Circulation
Book Subtitle: Anatomy, Mechanical Properties, and Biomechanics
Authors: Ghassan S. Kassab
DOI: https://doi.org/10.1007/978-3-030-14819-5
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2019
Hardcover ISBN: 978-3-030-14817-1Published: 28 May 2019
eBook ISBN: 978-3-030-14819-5Published: 15 May 2019
Edition Number: 1
Number of Pages: XVII, 564
Number of Illustrations: 122 b/w illustrations, 49 illustrations in colour
Topics: Cardiovascular Biology, Biomedical Engineering/Biotechnology, Biomedical Engineering and Bioengineering, Cardiology, Biomedicine general