Biomarkers in Inflammatory Bowel Diseases

  • Nik Sheng Ding
  • Peter De Cruz

Table of contents

  1. Front Matter
    Pages i-xvii
  2. James Rickard, Nik Sheng Ding, Peter De Cruz
    Pages 1-6
  3. Background to Biomarkers

    1. Front Matter
      Pages 7-7
    2. Zsuzsanna Kurti, Zsuzsanna Vegh, Lorant Gonczi, Peter L. Lakatos
      Pages 9-22
    3. Patrick B. Allen, Laurent Peyrin-Biroulet
      Pages 23-29
    4. Elizabeth A. Spencer, Marla C. Dubinsky
      Pages 31-44
    5. Anne S. Strik, Toer W. Stevens, Geert R. D’Haens
      Pages 45-53
  4. Clinical Algorithms Incorporating Predictive and Prognostic Biomarkers: Crohn’s Disease

    1. Front Matter
      Pages 55-55
    2. Amanda M. Lynn, Edward V. Loftus Jr
      Pages 57-71
    3. Satya V. Kurada, Florian Rieder
      Pages 73-87
    4. Kurvi Patwala, Peter De Cruz
      Pages 89-97
    5. Wing Yan Mak, Siew Chien Ng
      Pages 99-118
  5. Clinical Algorithms Incorporating Predictive and Prognostic Biomarkers: Ulcerative Colitis

    1. Front Matter
      Pages 119-119
    2. Matthew C. Choy, Dean Seah, Peter De Cruz
      Pages 121-130
    3. Rose Vaughan, Britt Christensen, David T. Rubin
      Pages 131-140
    4. Ian Craig Lawrance
      Pages 141-153
    5. Chang-Ho Ryan Choi, Ibrahim Al-Bakir
      Pages 155-167
    6. Jonathan P. Segal, Ailsa L. Hart
      Pages 169-180
  6. Clinical Algorithms Incorporating Predictive and Prognostic Biomarkers: Specialised Scenarios

    1. Front Matter
      Pages 181-181
    2. João Sabino, Joren tenHove, Joana Torres
      Pages 191-204
    3. Emma Flanagan, Sally Bell
      Pages 205-215
    4. Zubin Grover, Peter Lewindon
      Pages 217-231
    5. Ashish Srinivasan, Nik Sheng Ding, Daniel van Langenberg, Peter De Cruz
      Pages 243-255
    6. Petra Weimers, Dorit Vedel Ankersen, Pia Munkholm
      Pages 271-278
  7. Scientific Platforms for Biomarker Discovery

    1. Front Matter
      Pages 279-279
    2. Jakob Seidelin, Johan Burisch
      Pages 281-291
    3. Agathe Peyrottes, Phillippe Seksik, Joël Doré, Philippe Marteau
      Pages 293-301
    4. Maria Glymenaki, Jia V. Li, Julian R. Marchesi
      Pages 303-312
    5. Nurulamin M. Noor, Tim Raine
      Pages 313-321
    6. Nurulamin M. Noor, Miles Parkes, James C. Lee
      Pages 323-331
  8. Conclusion

  9. Back Matter
    Pages 359-365

About this book


This book provides a comprehensive and complete overview of biomarkers in clinical practice for inflammatory bowel disease (IBD) bringing together the literature in a clear and concise manner. The book bridges the gap between growing knowledge at the bench and current and future applications of biomarkers in clinical practice. 

The central structure of the book focuses on prognostic and predictive biomarkers in IBD with an emphasis on the fields of research and scientific techniques (genomics, proteomics and metabonomics) that have led to biomarker discovery and places these biomarkers within a clinical context to help understand their utility in clinical practice.

This book will be of use to clinicians who have an interest in using biomarkers in clinical practice as well as clinician researchers and scientists involved in the biomarker research pipeline.

The author team comprises experts from around the world in order to bring together the literature in an effort to inform clinicians and researchers about the current state-of-the art in biomarker discovery.  It is intended to  assist future research efforts and indicate how biomarkers might be best applied to clinical practice both at present and in the future


Inflammatory Bowel Disease Genomics Metatranscriptomics proteomics biomarkers fibrosis cholangitis ulcerative colits

Editors and affiliations

  • Nik Sheng Ding
    • 1
  • Peter De Cruz
    • 2
  1. 1.St Vincent’s Hospital, The University of MelbourneMelbourneAustralia
  2. 2.Austin Health, The University of MelbourneMelbourneAustralia

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Switzerland AG 2019
  • Publisher Name Springer, Cham
  • eBook Packages Medicine
  • Print ISBN 978-3-030-11445-9
  • Online ISBN 978-3-030-11446-6
  • Buy this book on publisher's site