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Table of contents

  1. Front Matter
    Pages 1-10
  2. Christina Bolander-Gouaille, Teodoro Bottiglieri
    Pages 11-13
  3. Christina Bolander-Gouaille, Teodoro Bottiglieri
    Pages 15-19
  4. Christina Bolander-Gouaille, Teodoro Bottiglieri
    Pages 21-33
  5. Christina Bolander-Gouaille, Teodoro Bottiglieri
    Pages 35-57
  6. Christina Bolander-Gouaille, Teodoro Bottiglieri
    Pages 59-108
  7. Christina Bolander-Gouaille, Teodoro Bottiglieri
    Pages 109-149
  8. Christina Bolander-Gouaille, Teodoro Bottiglieri
    Pages 151-161
  9. Christina Bolander-Gouaille, Teodoro Bottiglieri
    Pages 163-169
  10. Christina Bolander-Gouaille, Teodoro Bottiglieri
    Pages 171-182
  11. Back Matter
    Pages 183-219

About this book

Introduction

During the last 15 years the research on homocysteine and the vitamins involved in its metabolism has become very dynamic. About 1,500 publications on the subject are now published each year. The research has long mainly focused on the association between homocysteine and cardiovascular disease, but also pregnancy complications/ fetal malformations. There is, however, an increasing interest in the connection between the homocysteine metabolism and neuropsychiatric disease with a steeply increasing number of publications. In particular, the association between homocysteine metabolism and cognitive decline/dementia attracts much interest. If simple, non-toxic homocysteine-lowering treatment with vitamins can reduce the incidence of, or delay the onset of dementia, it would have an enormous impact in societies with a rapidly increasing number of elderly at risk for dementia. This book summarises the research within the neuropsychiatric field, but also gives an overview of the underlying biochemistry and of diagnostic aspects. About 1,000 references are given. Christina Bolander-Gouaille, a pharmacist, has for over 10 years specialised in writing reviews/monographs on homocysteine and related vitamins. This is her third book in a series edited by Springer Verlag. This book, however, is written in collaboration with Teodoro Bottiglieri, who is director of neuropharmacology and senior research scientist at Baylor University, Institute for Metabolic Diseases in Dallas, USA.

Keywords

Depression Vitamin B12 Vitamin B6 cobalamin dementia drug interactions enzyme defecte folate folic acid homocysteine lifestyle factors methylenetetrahydrofolate reductase neuropsychiatry pyridoxine riboflavine

Authors and affiliations

  • Christina Bolander-Gouaille
    • 1
  • Teodoro Bottiglieri
    • 2
  1. 1.HelsingborgSweden
  2. 2.Institute of Metabolic DiseaseBaylor University Medical Center3812 Elm StreetTexas

Bibliographic information

  • DOI https://doi.org/10.1007/978-2-287-69375-5
  • Copyright Information Springer-Verlag Paris 2007
  • Publisher Name Springer, Paris
  • Print ISBN 978-2-287-22558-1
  • Online ISBN 978-2-287-69375-5
  • Buy this book on publisher's site