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Atlas of Postmenopausal Osteoporosis

  • René Rizzoli

Table of contents

  1. Front Matter
    Pages i-ix
  2. Serge Ferrari, Johann D Ringe
    Pages 1-32
  3. Juliet Compston, Harry Genant
    Pages 33-60
  4. Patrick Ammann, René Rizzoli
    Pages 61-82
  5. Audrey Neuprez, Jean-Yves Reginster
    Pages 83-114
  6. René Rizzoli
    Pages 115-115
  7. Back Matter
    Pages 117-118

About this book

Introduction

René Rizzoli Menopause is the time in a woman’s life when reproductive capacity ends. Ovaries decrease their activity and the production of sex hormones ceases. This period may be associated with a large variety of symptoms affecting the cardiovascular and urogenital systems, as well as skin, hair and bone. Bone capital is accumulated by the end of the second decade and remains more or less constant up to the time of menopause. Sex hormone deficiency leads to accelerated bone turnover, a negative balance and microarchitectural deterioration, which compromises bone strength, thereby increasing bone fragility and, thus, fracture risk. By the age of 80, it is estimated that 50% of trab- ular bone will have been lost. Natural menopause occurs between the ages of 45 and 54 years all over the world. This age does not appear to have changed significantly over the centuries. In contrast, since the middle of the 19th century, life expectancy, particularly in women, has increased considerably, with most women living to the age of 80 years or more in many regions of the world. This means that at the age of 50 years, a woman will live for more than 30 years without bone protection by sex hormones. This r- resents more than one-third of a woman’s life. At the age of 50 years, the lifetime risk to experience a fracture is about 50% (ie, one out of two women will have a fracture during this period).

Keywords

atlas bone fracture osteoporosis postmenopausal

Editors and affiliations

  • René Rizzoli
    • 1
  1. 1.Division of Bone Diseases, Department of Rehabilitation and GeriatricsUniversity Hospitals, Faculty of MedicineGenevaSwitzerland

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-907673-28-3
  • Copyright Information Springer Healthcare Ltd. 2010
  • Publisher Name Springer Healthcare, Tarporley
  • eBook Packages Medicine
  • Print ISBN 978-1-85873-443-9
  • Online ISBN 978-1-907673-28-3
  • Buy this book on publisher's site