© 2010

Advances in Vascular Medicine

  • David Abraham
  • Handler Clive
  • Michael Dashwood
  • Gerry Coghlan
  • State-of-the-art papers by internationally acclaimed experts

  • Few books focus specifically on the developing field of molecular basis and clinical complications


Table of contents

  1. Front Matter
    Pages i-xviii
  2. Genetics and Gene Therapy

    1. Front Matter
      Pages 1-2
    2. Rachel Masson, Stuart A. Nicklin, Andrew H. Baker
      Pages 25-54
  3. Animal Models to Study Vascular Disease

    1. Front Matter
      Pages 56-56
    2. Mirko Manetti, Elena Neumann, Oliver Distler, Ulf Müller-Ladner
      Pages 57-75
    3. Christopher Jackson, Ulrike Benbow, Andrew Bond, Deborah Galley, Claire Schwartz
      Pages 77-91
    4. Karoline von Websky, Susi Heiden, Thiemo Pfab, Berthold Hocher
      Pages 93-101
  4. Molecules and Mediators and Therapeutic Applications

    1. Front Matter
      Pages 104-104
    2. Jeremy D. Pearson, Xu Shi-wen, Sarah L. Howat, Christopher P. Denton, David J. Abraham
      Pages 105-111
    3. Jonathan R. Murrow, Saurabh S. Dhawan, Arshed A. Quyyumi
      Pages 131-151
    4. Pedro D’Orléans-Juste, Dan Lacroix, Lucie Germain, François A. Auger
      Pages 153-174
    5. Maria S. Fernández-Alfonso, Marta Gil-Ortega, Beatriz Somoza
      Pages 175-186
    6. Muhiddin A. Ozkor, Jonathan R. Murrow, Arshed A. Quyyumi
      Pages 187-210
  5. Clinical Aspects of Vascular Biology

    1. Front Matter
      Pages 213-214
    2. Joanna Pepke-Zaba
      Pages 215-224
    3. Jay Suntharalingam, Nicholas W. Morrell
      Pages 225-231
    4. Charlotte Cash, Joanne Cleverley
      Pages 247-272

About this book


Understanding the many complex cellular and molecular mechanisms underlying human vascular diseases is essential in improving the management of patients with this clinically important and wide-ranging group of diseases. This is particularly important when considering the extent of this issue across the world.

Written by a team of world-renowned authorities, Advances in Vascular Medicine highlights some of the relationships between basic science and clinical medicine, and reviews both research and clinical practice methods and outcomes in vascular biology and pathobiology. It is an authoritative reference for these important topics of vascular biology and includes chapters that explain the clinical issues to the basic scientist as well as providing clinicians with a scientific grounding in vascular diseases. Although there is still much work to be done to advance understanding of vascular disease, the information and insights contained in this book are a vital contribution to the literature, giving scientists and clinicians the opportunity to learn more about this exciting field of biomedicine.


Bypass cardiovascular cells endothelium hypertension pathophysiology physiology surgery tissue

Editors and affiliations

  • David Abraham
    • 1
  • Handler Clive
    • 2
  • Michael Dashwood
    • 3
  • Gerry Coghlan
    • 4
  1. 1.University College LondonLondonUnited Kingdom
  2. 2.The Royal Free & Univ College Med SchoolLondonUnited Kingdom
  3. 3.University College LondonLondonUnited Kingdom
  4. 4.The Royal Free & Univ College Med SchoolLondonUnited Kingdom

About the editors

Professor David Abraham, Professor of Molecular Biology, University College London, London, UK.

Dr Clive Handler, Consultant in Pulmonary Hypertension, The Royal Free Hospital, and Honorary Senior Lecturer, The Royal Free and University College School of Medicine, London, UK.

Dr Michael Dashwood, Senior Lecturer in Biochemistry, University College London, London, UK.

Dr Gerry Coghlan, Consultant Cardiologist, The Royal Free Hospital, London, UK.

The Editors – two clinicians and two basic scientists, are all well known in their respective fields, and bring together this essential collaboration for this book dealing with scientific principles and clinical practice.

The Authors

These are world famous leaders and internationally acclaimed experts in the field.

Bibliographic information

  • Book Title Advances in Vascular Medicine
  • Editors David Abraham
    Clive Handler
    Michael Dashwood
    Gerry Coghlan
  • DOI
  • Copyright Information Springer-Verlag London 2010
  • Publisher Name Springer, London
  • eBook Packages Medicine Medicine (R0)
  • Hardcover ISBN 978-1-84882-636-6
  • Softcover ISBN 978-1-4471-5763-2
  • eBook ISBN 978-1-84882-637-3
  • Edition Number 1
  • Number of Pages XVIII, 451
  • Number of Illustrations 0 b/w illustrations, 0 illustrations in colour
  • Topics Cardiology
    Vascular Surgery
    Human Physiology
    Cardiac Surgery
  • Buy this book on publisher's site


From the reviews: “This collection presents focused discussions on the current understanding of endothelial function, atherosclerosis, pulmonary hypertension, systemic sclerosis, and chronic thromboembolic disease. … It is directed at a diverse audience of scientists and physicians who specialize in vascular disease. … provides clinical insight, which is useful for basic scientists and clinical researchers. It also offers vascular surgeons, cardiologists, rheumatologists, and vascular medicine physicians … . The high quality writing offers stimulating and relevant ideas to both investigators and clinicians.” (Judith L. Meadows, Doody’s Review Service, May, 2010)