Vascular Complications in Human Disease

Arterial disease and inflammation are fundamental causes of many medical conditions. Recently, there have been several major advances in our understanding of the causes of diseases affecting the heart, lungs, kidneys, skin and blood vessels. The role of endothelium derived growth factors, nitric oxide and other messengers in vascular disease has been more clearly defined. New treatments targeting these molecular disorders are being used with beneficial effects. Further progress depends on a combined approach embracing basic and clinical research so that treatments of common, important diseases can be designed intelligently and logically. "Vascular Complications in Human Disease" presents our understanding of vascular disease, in reviews of the main strands of basic and clinical research written by leading international experts. It also identifies routes for further fruitful research and development. This concise and carefully edited book, avoiding repetition, includes the full spectrum of basic research which is not covered in other textbooks.

• Bypass
• Lipoprotein
• angiogenesis
• atherosclerosis
• gene therapy
• genetics
• heart
• high-density lipoprotein (HDL)
• inflammation
• muscle
• prevention
• surgery
• vascular disease
• infectious diseases

From the reviews:

"This book on vascular biology as it relates to common complications of vascular diseases is divided into six sections addressing vascular complications in the pulmonary, renal, and cardiac systems as well as transplanted organs. … The book is aimed at both basic and clinical scientists as well as clinicians in several different specialties. … the book is most valuable for research scientists. … This is an excellent book for basic or clinical scientists … ." (Audrey Rosinberg, Doody’s Review Service, October, 2009)

• Royal Free and University College Medical School, London, UK

  David Abraham

• Clinical Biochemistry, Royal Free and University College Hospital Medical School, London, UK

  Michael Dashwood

• The National Pulmonary Hypertension Unit, Royal Free Hospital, London

  Clive Handler

• Department of Medicine, Royal Free and University College Hospital Medical School, London, UK

  Clive Handler

• Royal Free Hospital, London, UK

  Gerry Coghlan

Professor Dame Carol Black DBE, PRCP, President of the Royal College of Physicians, Professor and Head Of Academic and Clinical Department of Rheumatology, The Royal Free Hospital and University College London, UK.

Professor David Abraham PhD, Head of Research, Academic and Clinical Department of Rheumatology, The Royal Free Hospital and University College London, UK.

Dr Gerry Coghlan MD, Consultant Cardiologist, Director of the Pulmonary Hypertension Unit, The Royal Free Hospital, London, UK.

Dr Michael Dashwood, PhD, Senior Lecturer in Biochemistry, University College London, UK.

Dr Christopher Denton, PhD, Senior Lecturer and Consultant Rheumatologist, The Royal Free Hospital and University College London, UK.

Dr Clive Handler MD, Honorary Consultant, Pulmonary Hypertension Unit, The Royal Free Hospital, London, UK.

All the authors are internationally respected and leading clinical and basic scientists and clinicians.

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