Electrical Diseases of the Heart

Genetics, Mechanisms, Treatment, Prevention

  • Ihor Gussak
  • Charles Antzelevitch
  • Arthur A. M. Wilde
  • Paul A. Friedman
  • Michael J. Ackerman
  • Win-Kuang Shen

Table of contents

  1. Front Matter
    Pages i-xxvi
  2. Basic Foundations of Normal and Abnormal Cardiac Electrical Activity

    1. Front Matter
      Pages 1-1
    2. Isabelle Baró, Denis Escande†
      Pages 11-23
    3. Alex V. Postma, Vincent M. Christoffels, Antoon F.M. Moorman
      Pages 24-36
    4. Cristina Basso, Siew Yen Ho, Gaetano Thiene
      Pages 37-51
    5. Charles Antzelevitch, Alexander Burashnikov, José M. Di Diego
      Pages 65-132
    6. Shingo Murakami, Yoshihisa Kurachi
      Pages 133-144
    7. Simona Casini, Arthur A. M. Wilde, Hanno L. Tan
      Pages 170-186
    8. Yanfei Ruan, Raffaella Bloise, Carlo Napolitano, Silvia G. Priori
      Pages 187-193
    9. Nicolas Lindegger, Robert S. Kass
      Pages 194-206
    10. Andre Terzic, Michel Vivaudou, Christophe Moreau, Timothy M. Olson, Arshad Jahangir, Leonid V. Zingman et al.
      Pages 207-217
    11. Subeena Sood, Xander H.T. Wehrens
      Pages 218-231
    12. Matteo Vatta
      Pages 232-246
    13. Arshad Jahangir, Srinivasan Sattiraju, Win-Kuang Shen
      Pages 247-260
    14. Brett Burstein, Philippe Comtois, Stanley Nattel
      Pages 261-280

About this book


The past decade has witnessed an explosion of knowledge and radical changes in our understanding of the molecular, ionic, genetic, and pharmacologic basis of electrical diseases of the heart. Electrical diseases of the heart are heritable arrhythmogenic clinical entities that may share common clinical and genetic features, yet may be distinctly different in their genesis, prognosis, and management. Notably, both congenital and acquired electrical diseases of the heart are receiving increased recognition as a result of important advances in genetic analysis.

Electrical Diseases of the Heart is a thorough clinical reference on the current status of cardiac electrophysiological disease,emphasizing common and diverse clinical features. The latest developments in the field of experimental and clinical cardiac electrophysiology, genetics, pharmacology, and interventional therapies of various clinical arrhythmogenic entities are featured and discussed in terms of recent advances in basic and clinical science. Residents, fellows, and physicians in cardiology and electrophysiology will gain valuable insight into cardiac electrophysiology and clinical electrocardiology by reading this book, including expert review of the genetic and epidemiologic considerations, diagnostic and therapeutic modalities of the newly discovered clinical syndromes, and electrocardiographic phenomena, and their correlation with the most recent advances in the basic science.


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Editors and affiliations

  • Ihor Gussak
    • 1
    • 2
  • Charles Antzelevitch
    • 3
    • 4
  • Arthur A. M. Wilde
    • 5
  • Paul A. Friedman
    • 6
  • Michael J. Ackerman
    • 6
  • Win-Kuang Shen
    • 7
  1. 1.Cardiovascular Boehringer Ingelheim Pharmaceuticals RidgefieldUSA
  2. 2.Robert Wood Johnson Medical SchoolUniversity of Medicine and Dentistry of New JerseyBridgewaterUSA
  3. 3.Gordon K. Moe Scholar Masonic Medical Research LaboratoryUticaUSA
  4. 4.Upstate Medical UniversitySyracuseUSA
  5. 5.Heart Failure Research Center Department of Clinical and Experimental CardiologyAcademic Medical CenterAmsterdamThe Netherlands
  6. 6.Mayo Clinic College of MedicineRochesterUSA
  7. 7.Division of Cardiovascular DiseasesMayo Clinic College of MedicineRochesterUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-84628-854-8
  • Copyright Information Springer-Verlag London Limited 2008
  • Publisher Name Springer, London
  • eBook Packages Medicine
  • Print ISBN 978-1-84628-853-1
  • Online ISBN 978-1-84628-854-8
  • About this book