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Molecular Toxicology Protocols

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  • © 2014
  • Latest edition

Overview

  • Includes cutting-edge methods and protocols
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Methods in Molecular Biology (MIMB, volume 1105)

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About this book

Molecular Toxicology Protocols, Second Edition aims to bring together a series of articles describing validated methods to elucidate specific molecular aspects of toxicology, the emphasis being on the application of molecular methods to genetic toxicology. The volume is divided into ten parts, roughly corresponding to the spectrum of biomarkers intermediate between exposure and disease outcomes as proposed in molecular epidemiology models. Subjects of these new chapters range from preparation of fluid specimens for analysis of cellular inflammatory responses to genotoxic insults to sensitive methods for proteomic analysis and aberrant DNA methylation patterns. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and easily accessible, Molecular Toxicology Protocols, Second Edition addresses not only the needs of molecular biologists and toxicologists, but also those of individuals interested in applying molecular methods to clinical applications, such as geneticists, pathologists, biochemists, and epidemiologists. 

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Keywords

Table of contents (43 protocols)

  1. Toxicoproteomics

  2. Gene Promoter Methylation

  3. Array Technologies

  4. Analysis of DNA Adducts

  5. Detection of Chromosomal and Genome-Wide Damage

Editors and Affiliations

  • Occupational Health, University of Pittsburgh Dept. Environmental &, Pittsburgh, USA

    Phouthone Keohavong

  • Dept. of Pharmaceutical Sciences, Nova Southeastern University College of Pharmacy, Fort Lauderdale, USA

    Stephen G. Grant

Bibliographic Information

  • Book Title: Molecular Toxicology Protocols

  • Editors: Phouthone Keohavong, Stephen G. Grant

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-62703-739-6

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2014

  • Hardcover ISBN: 978-1-62703-738-9Published: 13 March 2014

  • Softcover ISBN: 978-1-4939-5654-8Published: 03 September 2016

  • eBook ISBN: 978-1-62703-739-6Published: 12 March 2014

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 2

  • Number of Pages: XV, 646

  • Number of Illustrations: 72 b/w illustrations, 29 illustrations in colour

  • Topics: Pharmacology/Toxicology, Human Genetics

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