Overview
- Describes comprehensive genetic toxicology protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 1044)
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Table of contents (24 protocols)
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Gene Mutation Assays
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Assays for Chromosomal Abnormalities
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Tests for Primary DNA Damage
Keywords
About this book
Genetic toxicology is recognized by geneticists and researchers concerned with the genetic impact of man-made chemicals. In Genotoxicity Assessment: Methods and Protocols, expert researchers in the field provide comprehensive genetic toxicology protocols. These include in vitro and in vivo protocols on mutation assays, cytogenetic techniques, and primary DNA damage, assays in alternate to animal models, and updated ICH guidelines. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, as well as key tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Genotoxicity Assessment: Methods and Protocols seeks to aid research students and scientists working in regulatory toxicology as well as biomedical, biochemical and pharmaceutical sciences.
Editors and Affiliations
Bibliographic Information
Book Title: Genotoxicity Assessment
Book Subtitle: Methods and Protocols
Editors: Alok Dhawan, Mahima Bajpayee
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-62703-529-3
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, New York 2013
Hardcover ISBN: 978-1-62703-528-6Published: 30 July 2013
Softcover ISBN: 978-1-4939-6302-7Published: 23 August 2016
eBook ISBN: 978-1-62703-529-3Published: 30 July 2013
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XV, 463
Number of Illustrations: 44 b/w illustrations, 62 illustrations in colour
Topics: Pharmacology/Toxicology, Human Genetics