Overview
- Covers both mammalian and non-mammalian model organisms
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
- Includes supplementary material: sn.pub/extras
Part of the book series: Methods in Molecular Biology (MIMB, volume 920)
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About this book
Current knowledge of the mechanisms that regulate DNA repair has grown significantly over the past years with technology advances such as RNA interference, advanced proteomics and microscopy as well as high throughput screens. The third edition of DNA Repair Protocols covers various aspects of the eukaryotic response to genomic insult including recent advanced protocols as well as standard techniques used in the field of DNA repair. Both mammalian and non-mammalian model organisms are covered in the book, and many of the techniques can be applied with only minor modifications to other systems than the one described. Written in the highly successful Methods in Molecular Biology? series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.
Thorough and intuitive, DNA Repair Protocols, Third Edition provides expert guidance for DNA repair, recombination, and replication.
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Keywords
Table of contents (40 protocols)
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Front Matter
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Identification of Repair Genes and Generation of Repair Mutants
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Front Matter
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Assessing DNA Damage and Repair
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Front Matter
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Repair of Incorrect or Damaged DNA Bases
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Front Matter
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Reviews
From the book reviews:
“This book covers important aspects of the eukaryotic response to genomic insults and the most recent and advanced protocols on DNA repair, recombination, and replication. … The intended audience is researchers in the field of DNA repair. In my judgment, graduate students, postdoctorals, and researchers in the field of molecular biology, especially those with a focus on DNA repair, will find this book extremely useful.” (Omer Iqbal, Doody’s Book Reviews, February, 2013)Editors and Affiliations
Bibliographic Information
Book Title: DNA Repair Protocols
Editors: Lotte Bjergbæk
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-61779-998-3
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2012
Hardcover ISBN: 978-1-61779-997-6Published: 01 September 2012
Softcover ISBN: 978-1-4939-5954-9Published: 23 August 2016
eBook ISBN: 978-1-61779-998-3Published: 23 October 2012
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 3
Number of Pages: XVII, 631
Topics: Human Genetics, Gene Function