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Animal Models of Acute Neurological Injuries II

Injury and Mechanistic Assessments, Volume 1

  • Book
  • © 2012

Overview

Editors:
  1. Jun Chen

    1. School of Medicine, University of Pittsburgh, Pittsburgh, USA

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  2. Xiao-Ming Xu

    1. School of Medicine, Stark Neurosciences Res. Inst., Indiana University, Indianapolis, USA

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    You can also search for this editor in PubMed   Google Scholar

  3. Zao C. Xu

    1. School of Medicine, Department of Anatomy & Cell Biology, Indiana University, Indianapolis, USA

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    You can also search for this editor in PubMed   Google Scholar

  4. John H. Zhang

    1. School of Medicine, Dept. Neurosurgery, Loma Linda University, Loma Linda, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Presents the material in a disease/disorder oriented manner for convenient reference
  • Offers both recommended, established techniques and alternative methods that have their own special utility
  • Features key tips and implementation advice to ensure successful results

Part of the book series: Springer Protocols Handbooks (SPH)

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Table of contents (56 protocols)

  1. General Neurobehavioral Assessments

    1. Emotional and Anxiety Assessments in CNS Disorders

      • Zaorui Zhao, Junfang Wu
      Pages 255-263

  2. General Neuroimaging Assessments

    1. Front Matter

      Pages 265-265
      Download chapter PDF

    2. Neuroimaging Assessment of Traumatic Brain Injury

      • Janna L. Harris, William M. Brooks
      Pages 267-280

    3. Imaging of Myelin by Coherent Anti-Stokes Raman Scattering Microscopy

      • Yan Fu, Ji-Xin Cheng
      Pages 281-291

  3. Subarachnoid Hemorrhage

    1. Front Matter

      Pages 293-293
      Download chapter PDF

    2. Grading Scales for Subarachnoid Hemorrhage

      • Andrew Losiniecki, Mario Zuccarello
      Pages 295-305

    3. Acute Physiologic and Morphologic Assessment Following Subarachnoid Hemorrhage

      • Vincent DiNapoli, Mario Zuccarello
      Pages 307-319

    4. Aneurysmal Subarachnoid Hemorrhage Grading in Animal Models

      • Robert Ayer, Takashi Sugawara, John H. Zhang
      Pages 321-330

    5. Physiological Assessments of Subarachnoid Hemorrhage

      • Jens P. Dreier
      Pages 331-338

    6. Spreading Depolarization

      • Clemens Reiffurth, Sergei A. Kirov, Jens P. Dreier
      Pages 339-352

    7. Assessment of Neurovascular Coupling

      • Cecilia Nicoletti, Nikolas Offenhauser, Devi Jorks, Sebastian Major, Jens P. Dreier
      Pages 353-372

    8. Assessment of Global Ischemia

      • Fatima A. Sehba, Joshua B. Bederson
      Pages 373-385

    9. Assessment of Microthromboembolism After Subarachnoid Hemorrhage

      • Mervyn D. I. Vergouwen, R. Loch Macdonald
      Pages 387-392

    10. Intracranial Pressure Assessments

      • Carla S. Jung, Andreas W. Unterberg
      Pages 393-399

    11. Assessment of Blood–Brain Barrier Breakdown

      • Yoash Chassidim, Ofer Prager, Ilan Shelef, Alon Friedman
      Pages 401-413

    12. Electrophysiology and Morris Water Maze to Assess Hippocampal Function After Experimental Subarachnoid Hemorrhage

      • Asma Tariq, R. Loch Macdonald
      Pages 415-424

    13. Biochemical and Molecular Biological Assessments of Subarachnoid Hemorrhage

      • Joseph F. Clark
      Pages 425-434

    14. Neurobehavioral Assessments of Subarachnoid Hemorrhage

      • Hidenori Suzuki, John H. Zhang
      Pages 435-440

    15. Neuroimaging Assessment of Subarachnoid Hemorrhage

      • Andre Obenaus, Sam Barnes
      Pages 441-455

  4. Cerebral Vasospasm

    1. Front Matter

      Pages 457-457
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Keywords

About this book

The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries.  Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system.  Volume 1 examines general assessments in morphology, physiology, biochemistry and molecular biology, neurobehavior, and neuroimaging, as well as extensive sections on subarachnoid hemorrhage, cerebral vasospasm, and intracerebral hemorrhage.  Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used.

 

Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.

Editors and Affiliations

  • School of Medicine, University of Pittsburgh, Pittsburgh, USA

    Jun Chen

  • School of Medicine, Stark Neurosciences Res. Inst., Indiana University, Indianapolis, USA

    Xiao-Ming Xu

  • School of Medicine, Department of Anatomy & Cell Biology, Indiana University, Indianapolis, USA

    Zao C. Xu

  • School of Medicine, Dept. Neurosurgery, Loma Linda University, Loma Linda, USA

    John H. Zhang

Bibliographic Information

  • Book Title: Animal Models of Acute Neurological Injuries II

  • Book Subtitle: Injury and Mechanistic Assessments, Volume 1

  • Editors: Jun Chen, Xiao-Ming Xu, Zao C. Xu, John H. Zhang

  • Series Title: Springer Protocols Handbooks

  • DOI: https://doi.org/10.1007/978-1-61779-576-3

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-61779-575-6Published: 18 May 2012

  • Softcover ISBN: 978-1-4939-6222-8Published: 23 August 2016

  • eBook ISBN: 978-1-61779-576-3Published: 17 May 2012

  • Series ISSN: 1949-2448

  • Series E-ISSN: 1949-2456

  • Edition Number: 1

  • Number of Pages: XVIII, 724

  • Number of Illustrations: 42 b/w illustrations, 125 illustrations in colour

  • Topics: Neurosciences, Neurology, Animal Models

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