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  • © 2012

Animal Models of Acute Neurological Injuries II

Injury and Mechanistic Assessments, Volume 1

  • Presents the material in a disease/disorder oriented manner for convenient reference

  • Offers both recommended, established techniques and alternative methods that have their own special utility

  • Features key tips and implementation advice to ensure successful results

Part of the book series: Springer Protocols Handbooks (SPH)

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eBook USD 149.00
Price excludes VAT (USA)
  • ISBN: 978-1-61779-576-3
  • Instant PDF download
  • Readable on all devices
  • Own it forever
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  • Tax calculation will be finalised during checkout
Softcover Book USD 189.00
Price excludes VAT (USA)
Hardcover Book USD 189.00
Price excludes VAT (USA)

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Table of contents (56 protocols)

  1. Front Matter

    Pages i-xviii
  2. General Morphological Assessments

    1. Front Matter

      Pages 1-1
    2. Assessment of Cell Death: Apoptosis, Necrosis, or In Between

      • Thomas Genetta, Ling Wei, Shan Ping Yu
      Pages 13-29
    3. The Stereology and 3D Volume Analyses in Nervous Tissue

      • Rabindra P. Singh, Li Shen, Feng C. Zhou
      Pages 31-52
  3. General Physiological Assessments

    1. Front Matter

      Pages 71-71
    2. Physiological Assessment in Stroke Research

      • Casey Lee Hall, Osama Mohamad, Shan Ping Yu, Ling Wei
      Pages 73-91
  4. General Biochemical and Molecular Biological Assessments

    1. Front Matter

      Pages 133-133
    2. Characterization of RNA

      • Marcel P. Van der Brug, Mar Matarin, Taura L. Barr
      Pages 135-160
    3. Protein Analysis

      • Anthony Kian-Fong Liou, Jun Chen
      Pages 171-186
    4. Application of Zymographic Methods to Study Matrix Enzymes Following Traumatic Brain Injury

      • Lesley K. Harris, Raiford T. Black, Thomas M. Reeves, Linda L. Phillips
      Pages 187-201
  5. General Neurobehavioral Assessments

    1. Front Matter

      Pages 203-203
    2. Rodent Behavioral Assessment in the Home Cage Using the SmartCage™ System

      • Xinmin Simon Xie, Jingxi Zhang, Bende Zou, James Xie, Jidong Fang, Nurulain T. Zaveri et al.
      Pages 205-222
    3. Assessment of Cognitive and Sensorimotor Deficits

      • Richard E. Hartman
      Pages 235-253

About this book

The successful previous volume on this topic provided a detailed benchwork manual for the most commonly used animal models of acute neurological injuries including cerebral ischemia, hemorrhage, vasospasm, and traumatic brain and spinal cord injuries.  Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments aims to collect chapters on assessing these disorders from cells and molecules to behavior and imaging. These comprehensive assessments are the key for understanding disease mechanisms as well as developing novel therapeutic strategies to ameliorate or even prevent damages to the nervous system.  Volume 1 examines general assessments in morphology, physiology, biochemistry and molecular biology, neurobehavior, and neuroimaging, as well as extensive sections on subarachnoid hemorrhage, cerebral vasospasm, and intracerebral hemorrhage.  Designed to provide both expert guidance and step-by-step procedures, chapters serve to increase understanding in what, why, when, where, and how a particular assessment is used.

 

Accessible and essential, Animal Models of Acute Neurological Injuries II: Injury and Mechanistic Assessments will be useful for trainees or beginners in their assessments of acute neurological injuries, for experienced scientists from other research fields who are interested in either switching fields or exploring new opportunities, and for established scientists within the field who wish to employ new assessments.

Keywords

  • Acute neurological injury
  • Animal models
  • Cerebral vasospasm
  • General assessments
  • Intracerebral hemorrhage
  • Morphological assessments
  • Neurobehavior
  • Neuroimaging
  • Subarachnoid hemorrhage

Editors and Affiliations

  • School of Medicine, University of Pittsburgh, Pittsburgh, USA

    Jun Chen

  • School of Medicine, Stark Neurosciences Res. Inst., Indiana University, Indianapolis, USA

    Xiao-Ming Xu

  • School of Medicine, Department of Anatomy & Cell Biology, Indiana University, Indianapolis, USA

    Zao C. Xu

  • School of Medicine, Dept. Neurosurgery, Loma Linda University, Loma Linda, USA

    John H. Zhang

Bibliographic Information

  • Book Title: Animal Models of Acute Neurological Injuries II

  • Book Subtitle: Injury and Mechanistic Assessments, Volume 1

  • Editors: Jun Chen, Xiao-Ming Xu, Zao C. Xu, John H. Zhang

  • Series Title: Springer Protocols Handbooks

  • DOI: https://doi.org/10.1007/978-1-61779-576-3

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media, LLC 2012

  • Hardcover ISBN: 978-1-61779-575-6

  • Softcover ISBN: 978-1-4939-6222-8

  • eBook ISBN: 978-1-61779-576-3

  • Series ISSN: 1949-2448

  • Series E-ISSN: 1949-2456

  • Edition Number: 1

  • Number of Pages: XVIII, 724

  • Number of Illustrations: 42 b/w illustrations, 125 illustrations in colour

  • Topics: Neuroscience, Neurology, Experimental Organisms

Buying options

eBook USD 149.00
Price excludes VAT (USA)
  • ISBN: 978-1-61779-576-3
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 189.00
Price excludes VAT (USA)
Hardcover Book USD 189.00
Price excludes VAT (USA)