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Expression Profiling in Neuroscience

  • Yannis Karamanos

Part of the Neuromethods book series (NM, volume 64)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Peter J. Gebicke-Haerter
    Pages 35-61
  3. Tyler Demarest, Nivetha Murugesan, Jennifer A. Macdonald, Joel S. Pachter
    Pages 63-75
  4. Yan W. Asmann, E. Aubrey Thompson, Jean-Pierre A. Kocher
    Pages 77-87
  5. Anton Zoubarev, Paul Pavlidis
    Pages 89-100
  6. Mohit Raja Jain, Tong Liu, Teresa L. Wood, Hong Li
    Pages 119-138
  7. Nicole Haverland, Pawel Ciborowski
    Pages 139-159
  8. Michel Salzet, Céline Mériaux, Julien Franck, Maxence Wistorski, Isabelle Fournier
    Pages 181-223
  9. Melinda Wojtkiewicz, Pawel Ciborowski
    Pages 225-244
  10. Gwenael Pottiez, Pawel Ciborowski
    Pages 245-270
  11. Gradimir N. Misevic, Gerard BenAssayag, Bernard Rasser, Philippe Sales, Jovana Simic-Krstic, Nikola Misevic et al.
    Pages 271-281
  12. Back Matter
    Pages 283-284

About this book

Introduction

Transcriptomics and proteomics, studying the profile of the expression of nucleic acids and proteins respectively, are increasingly applied to gain a mechanistic insight into a wide spectrum of investigation, and the use of expression profiling studies for the central nervous system and brain function aids in the understanding of neurodegenerative disorders and tumor development mechanisms.  In Expression Profiling in Neuroscience, expert researchers provide a survey of the most commonly used approaches in the field and scan the different ways of studying the central nervous system/brain environment through expression profiling.  The first part addresses the gene expression profiling of the brain at a large scale or to a specific cell type such as blood-brain barrier endothelium. Then, the second part describes the protein expression studies and the different technologies applied.  Written for the popular Neuromethods series, chapters include corresponding background information, tested laboratory protocols, and step-by-step methods for reproducible laboratory experiments.

 

Detailed and authoritative, Expression Profiling in Neuroscience presents the state-of-the-art techniques necessary to expand research further into this vital area of study.

Keywords

Brain function Central nervous system Expression profiling Gene expression Protein expression Proteomics Transcriptome studies

Editors and affiliations

  • Yannis Karamanos
    • 1
  1. 1., Laboratorie de Physiopathologie de la BaUniversité d'ArtoisLensFrance

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-61779-448-3
  • Copyright Information Springer Science+Business Media, LLC 2012
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-447-6
  • Online ISBN 978-1-61779-448-3
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site