Tissue Engineering in Regenerative Medicine

  • Harold S. Bernstein

Part of the Stem Cell Biology and Regenerative Medicine book series (STEMCELL)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Stem Cells

    1. Front Matter
      Pages 1-1
    2. Odessa Yabut, Harold S. Bernstein
      Pages 17-38
    3. Thach-Vu Ho, Grace Asuelime, Wendong Li, Yanhong Shi
      Pages 39-52
    4. Sowmya Viswanathan, Armand Keating
      Pages 53-74
  3. Biomaterials and the Extracellular Environment

    1. Front Matter
      Pages 75-75
    2. Sean P. Sheehy, Kevin Kit Parker
      Pages 77-97
    3. Nicholas R. Boyd, Richard L. Boyd, George P. Simon, David R. Nisbet
      Pages 99-122
    4. Kelly Clause, Jonathan Lam, Tatiana Segura, Thomas H. Barker
      Pages 123-140
  4. Engineered Tissue

    1. Front Matter
      Pages 141-141
    2. Masayuki Yamato, Sebastian Sjöqvist
      Pages 143-159
    3. Sharon S. Y. Wong, Harold S. Bernstein
      Pages 161-196
    4. Frédéric Trensz, Anthony Scimè, Guillaume Grenier
      Pages 197-209
    5. Narutoshi Hibino, Christopher Breuer, Toshiharu Shinoka
      Pages 211-220
    6. Sarindr Bhumiratana, Gordana Vunjak-Novakovic
      Pages 221-235
    7. Andrea R. Tan, Clark T. Hung
      Pages 237-250
    8. Daniel A. Hägg, Bhranti Shah, Jeremy J. Mao
      Pages 251-269
  5. Synthetic Organs

    1. Front Matter
      Pages 271-271
    2. Anthony Atala
      Pages 273-295
    3. Joan E. Nichols, Jean A. Niles, Joaquin Cortiella
      Pages 297-313
    4. Ji Bao, James Fisher, Scott L. Nyberg
      Pages 315-332
  6. Immune Response

    1. Front Matter
      Pages 333-333
    2. Gaetano Faleo, Qizhi Tang
      Pages 335-352
    3. Kerry A. Daly, Bryan N. Brown, Stephen F. Badylak
      Pages 353-375
  7. Animal Models

    1. Front Matter
      Pages 377-377
    2. Fernando A. Fierro, J. Tomas Egana, Chrisoula A. Toupadakis, Claire Yellowley, Hans-Günther Machens, Jan A. Nolta
      Pages 379-391
  8. Back Matter
    Pages 415-426

About this book


Over the past decade, significant advances in the fields of stem cell biology, bioengineering, and animal models have converged on the discipline of regenerative medicine. This volume provides a state-of-the-art report on tissue engineering toward the goals of tissue and organ restoration and regeneration. Examples from different organ systems are used to illustrate progress with growth factors to assist in tissue remodeling; the capacity of stem cells for restoring damaged tissues; novel synthetic biomaterials to facilitate cell therapy; transplantable tissue patches that preserve three-dimensional structure; synthetic organs generated in culture; aspects of the immune response to transplanted cells and materials; and the development of suitable animal models for non-human clinical trials. Throughout the chapters, the reader will observe a common theme of basic discovery informing clinical translation, and clinical studies in animals and humans guiding subsequent experiments at the bench.


Bernstein Biology Cell Engineering Medicine Regenerative Stem Tissue

Editors and affiliations

  • Harold S. Bernstein
    • 1
  1. 1.Eli and Edythe Broad Center of Regenerat, Department of PediatricsUCSF, Cardiovascular Research InstituteSan FranciscoUSA

Bibliographic information