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Methods for the Discovery and Characterization of G Protein-Coupled Receptors

  • Craig W. Stevens

Part of the Neuromethods book series (NM, volume 60)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. The G Protein-Coupled Receptor in the Genome

    1. Front Matter
      Pages 1-1
    2. Matthew N. Davies, David E. Gloriam, Darren R. Flower
      Pages 3-18
    3. Ying-Xian Pan, Steven Grinnell, Gavril W. Pasternak
      Pages 19-34
    4. Dmitri Proudnikov, Vadim Yuferov, Mary Jeanne Kreek
      Pages 35-47
    5. Cheol Kyu Hwang, Ping-Yee Law, Li-Na Wei, Horace H. Loh
      Pages 49-69
  3. The Trafficking of G Protein-Coupled Receptors

  4. The G Protein-Coupled Receptor on the Membrane

    1. Front Matter
      Pages 209-209
    2. Elisa Alvarez-Curto, Richard J. Ward, Graeme Milligan
      Pages 231-253
    3. Kok Choi Kong, Andrew B. Tobin, Adrian J. Butcher
      Pages 255-272
    4. Frederick J. Ehlert, Hinako Suga
      Pages 273-304
  5. The Regulation of G Protein-Coupled Receptors

    1. Front Matter
      Pages 321-321
    2. Laura M. Bohn, Patricia H. McDonald
      Pages 347-358
    3. Philippe Sarret, Louis Doré-Savard, Pascal Tétreault, Valérie Bégin-Lavallée, Marc-André Dansereau, Nicolas Beaudet
      Pages 379-402
  6. Back Matter
    Pages 421-428

About this book

Introduction

The goal of the characterization and discovery of G protein-coupled receptors, arguably the most important class of signaling molecules in humans and other vertebrates, has spawned numerous vital methodologies.  In Methods for the Discovery and Characterization of G Protein-Coupled Receptors, experts in the field present the very latest on the methods and technology used to characterize and discover novel mechanisms of GPCRs which, in many cases, can be used directly to design experiments for the reader’s particular GPCR of interest and their specific avenue of investigation. Divided into four convenient sections, this detailed volume covers GPCRs in the genome, trafficking of GPCRs, GPCRs on the membrane, as well as the regulation of these key receptors.  Chapters also feature an important section called “Future Directions” which gives the reader an insight into advances soon to be realized in each area. Written for the popular Neuromethods series, this book contains the kind of detailed description and implementation advice that is crucial for getting optimal results.

 

Authoritative and cutting-edge, Methods for the Discovery and Characterization of G Protein-Coupled Receptors serves as an ideal guide for scientists determined to further our knowledge of crucially important set of receptors.

Keywords

Alternative splicing GPCRs In silico identification Membrane Opioid receptors Polymorphisms Post-translational regulation Regulation Trafficking

Editors and affiliations

  • Craig W. Stevens
    • 1
  1. 1.Center for Health Sciences, College of Osteopathic MedicineOklahoma State UniversityTulsaUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-61779-179-6
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-61779-178-9
  • Online ISBN 978-1-61779-179-6
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • Buy this book on publisher's site