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Studies on Experimental Models

  • Samar Basu
  • Lars Wiklund

Table of contents

  1. Front Matter
    Pages i-xix
  2. Diabetes

    1. Front Matter
      Pages 1-1
    2. Maria D. Mesa, Concepcion M. Aguilera, Angel Gil
      Pages 39-60
  3. Cardiovascular

    1. Front Matter
      Pages 61-61
    2. Karthikeyan Krishnamurthy, Ragu Kanagasabai, Lawrence J. Druhan, Govindasamy Ilangovan
      Pages 105-130
    3. Ingvild Paur, Harald Carlsen, Rune Blomhoff
      Pages 157-184
  4. Neurology

    1. Front Matter
      Pages 185-185
    2. V. Jackson-Lewis, M. A. Tocilescu, R. DeVries, D. M. Alessi, S. Przedborski
      Pages 187-209
    3. Jaewon Chang, Sandra Siedlak, Paula Moreira, Akihiko Nunomura, Rudy J. Castellani, Mark A. Smith et al.
      Pages 211-220
    4. Olivier C. Maes, Howard M. Chertkow, Eugenia Wang, Hyman M. Schipper
      Pages 251-263
  5. Ocular Diseases

    1. Front Matter
      Pages 301-301
    2. Toshihiko Ueda, Takako Nakanishi, Kazushi Tamai, Shinichi Iwai, Donald Armstrong
      Pages 303-317
  6. Toxicology/Environmental

    1. Front Matter
      Pages 341-341
    2. Hyeyoung Kim, Young-Joon Surh
      Pages 343-370
    3. Kristin Fabre, William DeGraff, John A. Cook, Murali C. Krishna, James B. Mitchell
      Pages 371-397
    4. Ingrid Wiswedel, Wolfgang Augustin, Sven Quist, Harald Gollnick, Andreas Gardemann
      Pages 441-465
    5. Christina Yfanti, Søren Nielsen, Camilla Scheele, Bente Klarlund Pedersen
      Pages 521-529
    6. Mari Carmen Gomez-Cabrera, Fabian Sanchis-Gomar, Vladimir Essau Martinez-Bello, Sandra Ibanez-Sania, Ana Lucia Nascimento, Li Li Ji et al.
      Pages 531-542
  7. In Vitro/Tissue Culture

    1. Front Matter
      Pages 543-543
    2. Enrique Cadenas, Alberto Boveris
      Pages 545-562
    3. Zhenquan Jia, Soumya Saha, Hong Zhu, Yunbo Li, Hara P. Misra
      Pages 563-577
    4. Jean Cadet, Thierry Douki, Jean-Luc Ravanat
      Pages 579-604
    5. Soumya Saha, Zhenquan Jia, Dongmin Liu, Hara P. Misra
      Pages 621-635
    6. Tim Hofer, Tonje Engevik Eriksen, Espen Hansen, Ingrid Varmedal, Ida-Johanne Jensen, Jeanette Hammer-Andersen et al.
      Pages 637-657
  8. Back Matter
    Pages 681-698

About this book

Introduction

There is a widespread consensus that use of antioxidants as a therapeutic approach may counteract free radical mediated pathologies. However, the role of antioxidants in normal physiology and redox signaling is still in its infancy. Since oxidative stress is related to various diseases and pathologies, scientists are eager to study the disease in humans, but it is not always ethical to study all the aspects of the disease in humans. Thus, it becomes mandatory to study the disease process and the mechanisms behind it through experimental models which generally involve animals, in vitro/cell culture studies, primates and even humans to a certain extent. Studies on Experimental Models contains data on the experimental models or review of such models of oxidative stress in various diseases. It is structured into six sections, which are as follows: diabetes, cardiovascular, neurology, ocular diseases, toxicology/environmental and in vitro/tissue culture. Each section presents a sketch of models in humans, animals and in vitro methods. Taken together, they comprise a valuable reference for basic and clinical scientists, one aimed at contributing to the advancement of oxidative stress research using appropriate animal models.

Keywords

Antioxidant Experimental Models Oxidative Stress

Editors and affiliations

  • Samar Basu
    • 1
  • Lars Wiklund
    • 2
  1. 1.Dept. Health & Caring SciencesUniversity UppsalaUppsalaSweden
  2. 2.Dept. Surgical Sciences, Anaesthesiology, & Intensive CareUppsala University HospitalUppsalaSweden

Bibliographic information