Studies on Experimental Models

  • Samar Basu
  • Lars Wiklund

Table of contents

  1. Front Matter
    Pages i-xix
  2. Diabetes

    1. Front Matter
      Pages 1-1
    2. Maria D. Mesa, Concepcion M. Aguilera, Angel Gil
      Pages 39-60
  3. Cardiovascular

    1. Front Matter
      Pages 61-61
    2. Karthikeyan Krishnamurthy, Ragu Kanagasabai, Lawrence J. Druhan, Govindasamy Ilangovan
      Pages 105-130
    3. Ingvild Paur, Harald Carlsen, Rune Blomhoff
      Pages 157-184
  4. Neurology

    1. Front Matter
      Pages 185-185
    2. V. Jackson-Lewis, M. A. Tocilescu, R. DeVries, D. M. Alessi, S. Przedborski
      Pages 187-209
    3. Jaewon Chang, Sandra Siedlak, Paula Moreira, Akihiko Nunomura, Rudy J. Castellani, Mark A. Smith et al.
      Pages 211-220
    4. Olivier C. Maes, Howard M. Chertkow, Eugenia Wang, Hyman M. Schipper
      Pages 251-263
  5. Ocular Diseases

    1. Front Matter
      Pages 301-301
    2. Toshihiko Ueda, Takako Nakanishi, Kazushi Tamai, Shinichi Iwai, Donald Armstrong
      Pages 303-317

About this book


There is a widespread consensus that use of antioxidants as a therapeutic approach may counteract free radical mediated pathologies. However, the role of antioxidants in normal physiology and redox signaling is still in its infancy. Since oxidative stress is related to various diseases and pathologies, scientists are eager to study the disease in humans, but it is not always ethical to study all the aspects of the disease in humans. Thus, it becomes mandatory to study the disease process and the mechanisms behind it through experimental models which generally involve animals, in vitro/cell culture studies, primates and even humans to a certain extent. Studies on Experimental Models contains data on the experimental models or review of such models of oxidative stress in various diseases. It is structured into six sections, which are as follows: diabetes, cardiovascular, neurology, ocular diseases, toxicology/environmental and in vitro/tissue culture. Each section presents a sketch of models in humans, animals and in vitro methods. Taken together, they comprise a valuable reference for basic and clinical scientists, one aimed at contributing to the advancement of oxidative stress research using appropriate animal models.


Antioxidant Experimental Models Oxidative Stress

Editors and affiliations

  • Samar Basu
    • 1
  • Lars Wiklund
    • 2
  1. 1.Dept. Health & Caring SciencesUniversity UppsalaUppsalaSweden
  2. 2.Dept. Surgical Sciences, Anaesthesiology, & Intensive CareUppsala University HospitalUppsalaSweden

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-1-60761-955-0
  • Online ISBN 978-1-60761-956-7
  • About this book