Cancer Susceptibility

Methods and Protocols

  • Michelle Webb

Part of the Methods in Molecular Biology book series (MIMB, volume 653)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Identifying Cancer Susceptibility Genes

  3. Screening Cancer Susceptibility Genes

    1. Front Matter
      Pages 131-131
    2. Claude Houdayer, Virginie Moncoutier, Jérôme Champ, Jérémie Weber, Jean-Louis Viovy, Dominique Stoppa-Lyonnet
      Pages 147-180
    3. Jin Li, G. Mike Makrigiorgos
      Pages 207-219
    4. Gareth R. Evans, Fiona Lalloo
      Pages 237-247
    5. Pascaline Gaildrat, Audrey Killian, Alexandra Martins, Isabelle Tournier, Thierry Frébourg, Mario Tosi
      Pages 249-257
    6. Sergey G. Kuznetsov, Suhwan Chang, Shyam K. Sharan
      Pages 259-280

About this book

Introduction

Over the past two decades, spectacular advances have been made in our understanding of the molecular genetics of cancer, leading to the pursuit of identifying genes that, when mutated, result in an increased susceptibility to the disease. In Cancer Susceptibility: Methods and Protocols, experts in the field bring together the most recent technological developments for identifying and screening cancer susceptibility genes. Divided into two clear sections, the book begins with gene identification, which updates and informs scientists working at identifying novel cancer susceptibility genes, while the second part deals with mutation screening technologies that aid scientists and clinicians working to translate this knowledge into the clinic. Written in the highly successful Methods in Molecular Biology™ series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Cancer Susceptibility: Methods and Protocols is a timely collection that seeks to provide researchers with the tools to predict and combat this terrible disease.

Keywords

BRCA Gene identification Gene screening Haut Molecular genetics Mutation screening technologies genes genetics hybridization

Editors and affiliations

  • Michelle Webb
    • 1
  1. 1., School of Clinical Laboratory SciencesUniversity of ManchesterManchesterUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60761-759-4
  • Copyright Information Springer Science+Business Media, LLC 2010
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-758-7
  • Online ISBN 978-1-60761-759-4
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book