Overview
- Details ready-to-use guides to establish and interrogate human and animal models of autoimmune diseases
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 900)
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About this book
Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease. The second edition of Autoimmunity: Methods and Protocols researchers in the field detail many of the most up-to-date methods which are now commonly used to study autoimmunity. The first half the book focuses on methods and protocols used to assess immunological and biochemical pathways of diseases pathogenesis in human subjects. While the second half investigates treatment of inflammatory arthritis, experimental allergic encephalomyelitis (EAE), IDDM, scleroderma, and uveitis in animal models and assessment of genetic, immunological, and biochemical parameters underlying spontaneous or exogenous antigen-induced diseases. Written in the highly successful Methods in Molecular Biology(tm) series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.
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Through and intuitive, Autoimmunity: Methods and Protocols, Second Edition seeks to aid scientists in the autoimmunity field to extract new meaning of old models and developing new ones.
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Keywords
Table of contents (23 protocols)
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Front Matter
Editors and Affiliations
Bibliographic Information
Book Title: Autoimmunity
Book Subtitle: Methods and Protocols
Editors: Andras Perl
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-60761-720-4
Publisher: Humana Totowa, NJ
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media New York 2012
Hardcover ISBN: 978-1-60761-719-8Published: 30 August 2012
Softcover ISBN: 978-1-4939-5637-1Published: 23 August 2016
eBook ISBN: 978-1-60761-720-4Published: 30 August 2012
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 2
Number of Pages: XIV, 504
Topics: Immunology, Gene Therapy