Membrane Transporters in Drug Discovery and Development

Methods and Protocols

  • Qing Yan

Part of the Methods in Molecular Biology book series (MIMB, volume 637)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Ming Ren Yen, Jonathan S. Chen, Jose L. Marquez, Eric I. Sun, Milton H. Saier
    Pages 47-64
  3. Praveen M. Bahadduri, James E. Polli, Peter W. Swaan, Sean Ekins
    Pages 65-103
  4. Takeo Nakanishi, Douglas D. Ross, Keisuke Mitsuoka
    Pages 105-120
  5. Frances J. Sharom, Ronghua Liu, Balpreet Vinepal
    Pages 133-148
  6. Parul Khare, Aubrey R. White, Anuprao Mulakaluri, Stanley M. Parsons
    Pages 181-219
  7. Corey Westerfeld
    Pages 221-230
  8. Scott M. Landfear
    Pages 245-262
  9. Gabriel A. Cook, Stanley J. Opella
    Pages 263-275
  10. Audra A. McKinzie, Renae M. Ryan, Robert J. Vandenberg
    Pages 277-293
  11. Stefan Bröer
    Pages 295-310
  12. Frederick B. Loiselle, Joseph R. Casey
    Pages 311-331
  13. Tamer M. A. Mohamed, Florence M. Baudoin-Stanley, Riham Abou-Leisa, Elizabeth Cartwright, Ludwig Neyses, Delvac Oceandy
    Pages 333-342

About this book

Introduction

Studies of membrane transporters have had a great impact on our understanding of human diseases and the design of effective drugs. In Membrane Transporters in Drug Discovery and Development: Methods and Protocols, expert researchers provide practical methodologies of the ongoing research on membrane transporters, considering applications of transporter technologies in drug discovery and development.  Chapters include new and useful fields and methodologies, including pharmacogenomics, nutrigenomics, systems biology, bioinformatics, nuclear magnetic resonance (NMR), imaging, and quantitative real-time-PCR. Transporter studies in drug discovery and development for various diseases are discussed, including neuropsychiatric disorders, cardiovascular diseases, ophthalmic diseases, cancer, and diabetes. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Wide-ranging and current, Membrane Transporters in Drug Discovery and Development: Methods and Protocols delivers a collection of practical protocols that can be used immediately in the lab, along with critical surveys of key topics by leading researchers in the field.

Keywords

In silico PCR bioinformatics cells genome molecular biology physiology skeletal muscle

Editors and affiliations

  • Qing Yan
    • 1
  1. 1.PharmTaoSanta ClaraUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60761-700-6
  • Copyright Information Humana Press 2010
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-699-3
  • Online ISBN 978-1-60761-700-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book