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Lung Cancer:

Prevention, Management, and Emerging Therapies

  • Book
  • © 2010

Overview

Editors:
  1. David J. Stewart

    1. M. D. Anderson Cancer Center, University of Texas, Houston, U.S.A.

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  • Provides full coverage of established and emerging therapies, including novel targeted and antiangiogenic agents
  • Evaluates the mechanisms of drug resistance and the therapeutic potential of new targets
  • Integrates molecular biology into strategies for prevention and treatment of lung cancer
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Clinical Oncology (CCO)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xvi
    Download chapter PDF

  2. Molecular Pathology of Lung Cancer

    • Alejandro Corvalan, Ignacio I. Wistuba
    Pages 1-25

  3. Tumor Microenvironment

    • Tonya C. Walser, Jane Yanagawa, Edward Garon, Jay M. Lee, Steven M. Dubinett
    Pages 27-69

  4. Racial and Ethnic Diversity in Lung Cancer

    • Carol J. Etzel, Sumesh Kachroo
    Pages 71-85

  5. Pharmacogenetics of Lung Cancer

    • Xifeng Wu, Jian Gu
    Pages 87-106

  6. Lung Cancer Prevention

    • Nir Peled, Robert L. Keith, Fred R. Hirsch
    Pages 107-138

  7. Adjuvant and Neoadjuvant Therapy of NSCLC

    • Katherine Pisters
    Pages 139-159

  8. Chemoradiotherapy for Inoperable Non-small Cell Lung Cancer

    • James D. Cox, David J. Stewart
    Pages 161-175

  9. Management of Advanced Non-small Cell Lung Cancer: Front Line Treatment

    • William N. William Jr., David J. Stewart
    Pages 177-194

  10. Chemotherapy in Previously Treated Patients with Non-small Cell Lung Cancer

    • Frank V. Fossella
    Pages 195-204

  11. Epidermal Growth Factor Receptor Inhibitors in the Treatment of Non-small Cell Lung Cancer

    • Paul Wheatley-Price, Frances A. Shepherd
    Pages 205-226

  12. Angiogenesis Inhibitors in Lung Cancer

    • Leora Horn, Alan Sandler
    Pages 227-252

  13. Other Molecular Targeted Agents in Non-small Cell Lung Cancer

    • Benjamin Besse, Jean-Charles Soria
    Pages 253-278

  14. Vaccine Therapy for Lung Cancer

    • John Nemunaitis, Jack Roth
    Pages 279-303

  15. Gene-Based Therapies for Lung Cancer

    • John Nemunaitis, Jack Roth
    Pages 305-330

  16. Lung Cancer Resistance to Chemotherapy

    • David J. Stewart
    Pages 331-393

  17. Small Cell Carcinoma of the Lung

    • Emer O. Hanrahan, Bonnie Glisson
    Pages 395-434

  18. Mesothelioma

    • Mary Frances McAleer, Reza J. Mehran, Anne Tsao
    Pages 435-465

  19. Advances in Oncology Clinical Research: Statistical and Study Design Methodologies

    • B. Nebiyou Bekele
    Pages 467-481

  20. Palliative Care for Patients with Lung Cancer

    • David Hui, Eduardo Bruera
    Pages 483-502
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Keywords

About this book

Defining the Lung Cancer Problem 1 Lung cancer is the leading cause of cancer death in the world. It kills almost as many Americans as cancers of the breast, prostate, colon, rectum, pancreas, and 2 kidney combined, and accounts for 28.6% of all US cancer deaths. With an increase in the 5-year relative survival rate from 13% to only 16% in the more than 2 30 years from 1974 to the present, it will take us another 840 years to eradicate lung cancer deaths if we do not improve the current rate of progress. As discussed in this text, lung cancer prevention has received substantial att- tion. The decrease in smoking in recent decades has helped, but smoking is not the only problem. Lung cancer in people who have never smoked is currently the 5th 3 leading cause of cancer death in the United States. Several factors contribute to the lethality of lung cancer, including the rapidity of tumor growth, advanced stage at diagnosis (due to nonspecificity of early sy- toms and the uncertain efficacy of screening), early development of metastases, and resistance to therapy. Several chapters in this book discuss new molecular targets that may be potentially exploitable in the future, as well as discussing our track record to date in exploiting them.

Reviews

From the reviews:

“This comprehensive review of prevention and treatment strategies for malignancies of the thorax thoroughly investigates tumor biology and discusses established and emerging therapies. … The book is written for a wide audience that includes pathologists, pulmonologists, medical oncologists, radiation oncologists, and surgical oncologists. … I would highly recommend this book to anyone interested in current and future therapies for lung cancer. This is one of the most comprehensive and up-to-date accounts of the field.” (Nagendra S. Koneru, Doody’s Review Service, July, 2010)

Editors and Affiliations

  • M. D. Anderson Cancer Center, University of Texas, Houston, U.S.A.

    David J. Stewart

Bibliographic Information

  • Book Title: Lung Cancer:

  • Book Subtitle: Prevention, Management, and Emerging Therapies

  • Editors: David J. Stewart

  • Series Title: Current Clinical Oncology

  • DOI: https://doi.org/10.1007/978-1-60761-524-8

  • Publisher: Humana Totowa, NJ

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Humana Press 2010

  • Hardcover ISBN: 978-1-60761-523-1Published: 04 March 2010

  • Softcover ISBN: 978-1-61779-684-5Published: 06 April 2012

  • eBook ISBN: 978-1-60761-524-8Published: 10 March 2010

  • Series ISSN: 2364-1134

  • Series E-ISSN: 2364-1142

  • Edition Number: 1

  • Number of Pages: XVI, 538

  • Number of Illustrations: 16 b/w illustrations, 14 illustrations in colour

  • Topics: Pneumology/Respiratory System, Oncology, Radiotherapy, Medical Biochemistry

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