Clinical Applications of Mass Spectrometry

Methods and Protocols

  • Uttam Garg
  • Catherine A. Hammett-Stabler

Part of the Methods in Molecular Biology book series (MIMB, volume 603)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Catherine A. Hammett-Stabler, Uttam Garg
    Pages 1-7
  3. Bruce A. Goldberger, Chris W. Chronister, Michele L. Merves
    Pages 75-87
  4. Jeff M. Knoblauch, David K. Scott, Laurie D. Smith, Uttam Garg
    Pages 121-128

About this book


As mass spectrometric methods now offer a level of specificity and sensitivity unrealized by spectrophotometric- and immunoassay-based methods, mass spectrometry has entered the clinical laboratory where it is being used for a wide range of applications. In Clinical Applications of Mass Spectrometry: Methods and Protocols, expert researchers provide detailed step-by-step procedures for the analysis of number of analytes of clinical importance. This versatile and expansive volume covers mass spectrometry methods for analytes including a variety of drugs, hormones, and metabolic compounds spanning the disciplines of toxicology, therapeutic drug monitoring, endocrinology, and pediatric metabolism. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to the analytes, lists of the necessary materials and reagents, readily reproducible analytical protocols, and detailed notes on troubleshooting and avoiding known pitfalls.

Comprehensive and dependable, Clinical Applications of Mass Spectrometry: Methods and Protocols offers its readers a wide array of valuable methods for experienced mass spectrometric labs that are looking to introduce new analyses as well as for those laboratories currently considering the addition of this resourceful and vital technology.


Clinical analytes Drugs Ethylen Gas chromatography Hormones LC-MS or GC-MS Liquid chromatography Mass Spectrometry Metabolic compounds indomethacin

Editors and affiliations

  • Uttam Garg
    • 1
  • Catherine A. Hammett-Stabler
    • 2
  1. 1.Dept. Pathology & Laboratory MedicineChildren's Mercy HospitalKansas CityU.S.A.
  2. 2.Dept. Pathology & Laboratory MedicineUniversity of North CarolinaChapel HillU.S.A.

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2010
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-458-6
  • Online ISBN 978-1-60761-459-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book