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Clinical Applications of Mass Spectrometry

Methods and Protocols

  • Uttam Garg
  • Catherine A. Hammett-Stabler

Part of the Methods in Molecular Biology book series (MIMB, volume 603)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Catherine A. Hammett-Stabler, Uttam Garg
    Pages 1-7
  3. Bruce A. Goldberger, Chris W. Chronister, Michele L. Merves
    Pages 75-87
  4. Jeff M. Knoblauch, David K. Scott, Laurie D. Smith, Uttam Garg
    Pages 121-128
  5. Mark M. Kushnir, Alan L. Rockwood, Bingfang Yue, A. Wayne Meikle
    Pages 219-228
  6. Patricia M. Jones, Michael J. Bennett
    Pages 229-243
  7. Bruce A. Goldberger, Chris W. Chronister, Michele L. Merves
    Pages 245-252
  8. X. Kate Zhang, Carole S. Elbin, Frantisek Turecek, Ronald Scott, Wei-Lien Chuang, Joan M. Keutzer et al.
    Pages 339-350
  9. Catherine A. Hammett-Stabler, Diane Ciuffetti Geis, James C. Ritchie, Christine Papadea
    Pages 379-387
  10. Bingfang Yue, Mark M. Kushnir, Francis M. Urry, Alan L. Rockwood
    Pages 389-398
  11. Bruce A. Goldberger, Chris W. Chronister, Michele L. Merves
    Pages 399-410
  12. Bruce A. Goldberger, Chris W. Chronister, Michele L. Merves
    Pages 453-460
  13. Robert L. Fitzgerald, Terrance L. Griffin, David A. Herold
    Pages 489-500

About this book

Introduction

As mass spectrometric methods now offer a level of specificity and sensitivity unrealized by spectrophotometric- and immunoassay-based methods, mass spectrometry has entered the clinical laboratory where it is being used for a wide range of applications. In Clinical Applications of Mass Spectrometry: Methods and Protocols, expert researchers provide detailed step-by-step procedures for the analysis of number of analytes of clinical importance. This versatile and expansive volume covers mass spectrometry methods for analytes including a variety of drugs, hormones, and metabolic compounds spanning the disciplines of toxicology, therapeutic drug monitoring, endocrinology, and pediatric metabolism. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to the analytes, lists of the necessary materials and reagents, readily reproducible analytical protocols, and detailed notes on troubleshooting and avoiding known pitfalls.

Comprehensive and dependable, Clinical Applications of Mass Spectrometry: Methods and Protocols offers its readers a wide array of valuable methods for experienced mass spectrometric labs that are looking to introduce new analyses as well as for those laboratories currently considering the addition of this resourceful and vital technology.

Keywords

Clinical analytes Drugs Ethylen Gas chromatography Hormones LC-MS or GC-MS Liquid chromatography Mass Spectrometry Metabolic compounds indomethacin

Editors and affiliations

  • Uttam Garg
    • 1
  • Catherine A. Hammett-Stabler
    • 2
  1. 1.Dept. Pathology & Laboratory MedicineChildren's Mercy HospitalKansas CityU.S.A.
  2. 2.Dept. Pathology & Laboratory MedicineUniversity of North CarolinaChapel HillU.S.A.

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60761-459-3
  • Copyright Information Humana Press 2010
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60761-458-6
  • Online ISBN 978-1-60761-459-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site