Wnt Signaling

  • Elizabeth Vincan

Part of the Methods in Molecular Biology book series (MIMB, volume 469)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Introduction

    1. Jenifer C. Croce, David R. McClay
      Pages 3-18
  3. Dictyostelium

  4. Cnidarians

    1. Thomas W. Holstein
      Pages 47-54
    2. Shalika Kumburegama, Naveen Wijesena, Athula H. Wikramanayake
      Pages 55-67
    3. Hans Bode, Tobias Lengfeld, Bert Hobmayer, Thomas W. Holstein
      Pages 69-84
  5. C. Elegans

    1. Samantha Van Hoffelen, Michael A. Herman
      Pages 87-102
    2. Daniel J. Marston, Minna Roh, Amanda J. Mikels, Roel Nusse, Bob Goldstein
      Pages 103-111
  6. Drosophila

    1. Foster C. Gonsalves, Ramanuj DasGupta
      Pages 115-125
    2. Kevin Legent, Jessica E. Treisman
      Pages 141-161
    3. Ramanuj DasGupta, Foster C. Gonsalves
      Pages 163-184
  7. Sea Urchin

    1. Shalika Kumburegama, Athula H. Wikramanayake
      Pages 187-199
    2. Joanna M. Bince, Chieh-fu Peng, Athula H. Wikramanayake
      Pages 201-211
  8. Zebrafish

    1. Heather Verkade, Joan K. Heath
      Pages 225-251
    2. Elizabeth L. Christie, Adam C. Parslow, Joan K. Heath
      Pages 253-272
    3. Benjamin M. Hogan, Heather Verkade, Graham J. Lieschke, Joan K. Heath
      Pages 273-300

About this book


Since their discovery, Wnt signaling molecules have been shown to control key events in embryogenesis, to maintain tissue homeostasis in the adult and, when aberrantly activated, to promote human degenerative diseases and cancer, thus making them a vital area of study.  Wnt Signaling: Methods and Protocols examines both biochemical assays and vertebrate and invertebrate model systems to provide a point of reference to current molecular protocols and the diverse model systems employed to study this important signaling pathway.  In Volume 2, Pathway Models, the diverse vertebrate and invertebrate models that have shaped the Wnt signaling field are described, presenting an overview of the unique properties of each organism, like asymmetric cell division in C. elegans and epithelial morphogenesis in Dictyostelium, with respect to studying Wnt/FZD function.  As a volume in the highly successful Methods in Molecular Biology™ series, chapters contain readily reproducible laboratory protocols, complete with lists of necessary equipment and reagents and the Notes section, which reveals helpful troubleshooting tips.


Comprehensive and cutting-edge, Wnt Signaling: Methods and Protocols collects the expertise and knowledge of many leaders in the field to produce this invaluable two-volume resource. 


Degenerative diseases and cancer Embryogenesis Hydra Invertebrate models Regulation Termination Tissue homeostasis Vertebrate models Wnt/FZD function Xenopus cell division gene expression genes hybridization molecular biology

Editors and affiliations

  • Elizabeth Vincan
    • 1
  1. 1.University of MelbourneParkvilleAustralia

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60327-469-2
  • Copyright Information Humana Press 2009
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60327-468-5
  • Online ISBN 978-1-60327-469-2
  • Series Print ISSN 1064-3745
  • About this book