Genetic Epidemiology

  • M. Dawn Teare

Part of the Methods in Molecular Biology book series (MIMB, volume 713)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Mohammed-Elfatih Twfieg, M. Dawn Teare
      Pages 3-12
    3. M. Dawn Teare, Mauro F. Santibàñez Koref
      Pages 13-25
    4. Cother Hajat
      Pages 27-39
  3. Genetic Linkage Mapping

    1. Front Matter
      Pages 41-41
    2. Kristina Allen-Brady, Nicola J. Camp
      Pages 43-53
    3. M. Dawn Teare
      Pages 55-67
  4. Genetic Mapping by Association

    1. Front Matter
      Pages 69-69
    2. Mark M. Iles
      Pages 89-103
    3. M. Dawn Teare
      Pages 105-117
    4. Frank Dudbridge
      Pages 119-127
    5. Andrew Collins, William J. Tapper
      Pages 129-139
  5. Emerging Themes

    1. Front Matter
      Pages 141-141
    2. Jaakko Kaprio, Karri Silventoinen
      Pages 143-152
    3. Nuala A. Sheehan, Sha Meng, Vanessa Didelez
      Pages 153-166
    4. Louise V. Wain, Martin D. Tobin
      Pages 167-183
    5. Kevin Walters
      Pages 185-197
  6. Case Studies

    1. Front Matter
      Pages 199-199

About this book

Introduction

Arising from firm foundations laid by mathematical population genetics, clinical genetics, and statistical epidemiology, genetic epidemiology attempts to identify the many components of risk

attributable to genes, environments, and interactions, and the course of its research can follow many diverse paths.  In Genetic Epidemiology, the success of genome-wide association studies in their identification of hundreds of disease susceptibility loci has inspired renowned experts to contribute thorough methodologies, which aim to bring together bioinformaticians, geneticists, clinicians, statisticians, and epidemiologists in the study of this vital field.  The volume opens with chapters covering the basics; however, it quickly moves on to coverage of more specialist topics such as twin studies, Mendelian randomization, genetic association studies, more advanced areas, as well as case studies.  As a part of the highly successful Methods in Molecular Biology™ series, this work provides the detailed description of the application and analysis of the most commonly employed methods that are necessary for a firm grounding in the field.

 

Authoritative and cutting-edge, Genetic Epidemiology aims to provide a basic framework for crucial interdisciplinary communication and understanding suited to newcomers to the field as well as experienced researchers and graduate level students.

Keywords

Bioinformatics Biostatistics Gene mapping Genetic association studies Genetic linkage analysis Genomic web resources Molecular genetics Risk assessment

Editors and affiliations

  • M. Dawn Teare
    • 1
  1. 1.School of Health and Related Research, Health Services ResearchUniversity of SheffieldSheffieldUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-60327-416-6
  • Copyright Information Springer Science+Business Media, LLC 2011
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60327-415-9
  • Online ISBN 978-1-60327-416-6
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book