Methods and Protocols

  • Arpad Szallasi

Part of the Methods in Molecular Biology book series (MIMB, volume 617)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Louise M. Steele, Margaret M. Sedensky, Phil G. Morgan
    Pages 1-17
  3. Hyangin Kim, Backil Sung, Jianren Mao
    Pages 31-39
  4. Janel M. Boyce-Rustay, Prisca Honore, Michael F. Jarvis
    Pages 41-55
  5. David J. Matson, Daniel C. Broom, Daniel N. Cortright
    Pages 67-78
  6. S. Stevens Negus, Edward J. Bilsky, Gail Pereira Do Carmo, Glenn W. Stevenson
    Pages 79-91
  7. Asma Khan, Kenneth M. Hargreaves
    Pages 93-104
  8. Silvia Benemei, Francesco De Cesaris, Paola Nicoletti, Serena Materazzi, Romina Nassini, Pierangelo Geppetti
    Pages 105-114
  9. Mia Karpitschka, Martin E. Kreis
    Pages 115-154
  10. James G. Modir, Mark S. Wallace
    Pages 159-164
  11. James G. Modir, Mark S. Wallace
    Pages 165-168
  12. Stephen A. Cooper, Paul J. Desjardins
    Pages 175-190
  13. Florian Steiner, Sraboni Ghose, Urs Thomet
    Pages 209-221
  14. Tamara Rosenbaum, Sidney A. Simon, Leon D. Islas
    Pages 223-236
  15. Alexandru Babes, Michael J. M. Fischer, Gordon Reid, Susanne K. Sauer, Katharina Zimmermann, Peter W. Reeh
    Pages 237-259

About this book


Chronic pain is a complex phenomenon, which continues to remain undertreated in the majority of affected patients thus representing a significant unmet medical need, but the development of cellular, subcellular, and molecular methods of approaching this epidemic of pain shows great promise. In Analgesia: Methods and Protocols, experts in the field present thorough coverage of molecular analgesia research methods from target discovery through target validation and clinical testing to tolerance and dependence, with extensive chapters on emerging receptor classes as targets for analgesic drugs and innovative analgesic strategies. As a volume in the highly successful Methods in Molecular Biology™ series, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes sections with tips on troubleshooting and avoiding known pitfalls.

Comprehensive and essential, Analgesia: Methods and Protocols promises to aid and enrich the research of all those scientists and clinicians who are interested in what the increasingly molecular future has in store for analgesia research, from the molecular research bench through the animal laboratory to the bedside.


Analgesic drugs Chronic pain PCR Personalized medicine Single nucleotide polymorphisms (SNPs) Target discovery and validation Transplantation gene expression genes genetics opioid

Editors and affiliations

  • Arpad Szallasi
    • 1
  1. 1.Dept. PathologyMonmouth Medical CenterLong BranchUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC 2010
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-60327-322-0
  • Online ISBN 978-1-60327-323-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book