Arthritis Research

Methods and Protocols Volume 1

  • Andrew P. Cope

Part of the Methods in Molecular Medicine book series (MIMM, volume 135)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Synovial Joint Morphology, Histopathology, and Immunohistochemistry

    1. Front Matter
      Pages 1-1
    2. Ai Lyn Tan, Helen I. Keen, Paul Emery, Dennis McGonagle
      Pages 3-26
    3. Richard J. Reece
      Pages 27-45
    4. Martina Gogarty, Oliver FitzGerald
      Pages 47-63
    5. Stefan Kuchen, Christian A. Seemayer, Michel Neidhart, Renate E. Gay, Steffen Gay
      Pages 65-75
    6. Jörg H. W. Distler, Oliver Distler, Michel Neidhart, Steffen Gay
      Pages 77-90
    7. Ulf Müller-Ladner, Martin Judex, Elena Neumann, Steffen Gay
      Pages 91-104
    8. Jonathan T. Beech, Fionula M. Brennan
      Pages 105-119
    9. Pascal O. van der Hall, Maarten C. Kraan, Paul Peter Tak
      Pages 121-143
  3. Cartilage Matrix and Bone Biology

    1. Front Matter
      Pages 145-145
    2. Ernst B. Hunziker
      Pages 147-166
    3. Barbara Osborn, Yun Bai, Anna H. K. Plaas, John D. Sandy
      Pages 167-182
    4. Samantha N. Redman, Ilyas M. Khan, Simon R. Tew, Charles W. Archer
      Pages 183-199
    5. John S. Mort, Peter J. Roughley
      Pages 201-209
    6. Tim E. Cawston, Tanya G. Morgan
      Pages 211-226
    7. Rosalind M. Hembry, Susan J. Atkinson, Gillian Murphy
      Pages 227-238
    8. Richard D. Evans, Yoshifumi Itoh
      Pages 239-249
    9. Linda Troeberg, Hideaki Nagase
      Pages 251-267
    10. Georg Schett, Birgit Tuerk
      Pages 269-283

About this book


Arthritis Research: Methods and Protocols is a compendium of data pertinent to the methods and protocols that have contributed to recent advances in molecular medicine in general, but to the molecular basis of rheumatic disease in particular. These volumes details novel technologies, some of which are still evolving and whose impacts are yet to be determined. Leaders in the field contribute to cover such exciting and cutting edge topics as imaging and immunohistochemistry, analysis of cartilage and bone catabolism, immunobiology, and cell trafficking.

In Volume 1, authors discuss synovial joint morphology, histopathology, and immunohistochemistry, cartilage matrix and bone biology, and cell trafficking, migration and invasion. Volume 2 is broken up into sections that cover immunobiology and T cells, animal models of arthritis, and applications of new technologies, such as Differential Display Reverse Transcription-Polymerase Chain Reaction (DDRT-PCR), to define novel therapeutic targets. Both volumes combine to produce a concise set of protocols condensing decades of experience and expertise.

Arthritis Research: Methods and Protocols will be a valuable tool for basic research investigators, clinician scientists, pathologists, immunologists, and biochemists looking to stay current in their fields.


Arthritis PCR gene expression gene transfer genes hybridization microscopy transcription

Editors and affiliations

  • Andrew P. Cope
    • 1
  1. 1.The Kennedy Institute of RheumatologyImperial College LondonLondonUK

Bibliographic information

  • DOI
  • Copyright Information Humana Press 2007
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-344-2
  • Online ISBN 978-1-59745-401-8
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • About this book