New Antibiotic Targets

  • W. Scott Champney

Part of the Methods In Molecular Medicine™ book series (MIMM, volume 142)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Kishore R. Sakharkar, Meena K. Sakharkar, Vincent T. K. Chow
    Pages 1-9
  3. Michelle M. Butler, George E. Wright
    Pages 25-36
  4. Beyer Dieter, Peter Kroll Hein, Heike Brötz-Oesterhelt
    Pages 53-61
  5. Abdalla Al Refaii, Alix Jean-Hervé
    Pages 75-85
  6. Letizia Brandi, John Dresios, Claudio O. Gualerzi
    Pages 87-106
  7. Alexander S. Mankin, Norbert Polacek
    Pages 107-116
  8. Kiet T. Nguyen, Dehua Pei
    Pages 117-130
  9. Michael J. Pucci, Thomas J. Dougherty
    Pages 131-141
  10. Hernick Marcy, Fierke Carol A.
    Pages 143-154
  11. Barbara J. Kamicker, Michael T. Sweeney, Frank Kaczmarek, Fadia Dib-Haj, Wenchi Shang, Kim Crimin et al.
    Pages 187-204
  12. Stephen Douthwaite, Rikke Lind Jensen, Finn Kirpekar
    Pages 223-237
  13. Thammaiah Viswanatha, Laura Marrone, Valerie Goodfellow, Gary I. Dmitrienko
    Pages 239-260

About this book

Introduction

A crisis is developing in the treatment of infectious diseases, with microorganisms frequently showing resistance to currently prescribed antibiotics. Fewer and fewer antimicrobial agents are now available to treat these infections. In "New Antibiotic Targets," W. Scott Champney examines specific techniques which can be used to explore new drug targets and the effectiveness of new antibiotics. By testing new antimicrobial agents and modified existing drugs, the most vulnerable cell processes, such as cell wall and membrane synthesis, DNA replication, RNA transcription and protein synthesis, can be better exploited. This in-depth volume, however, delves even deeper by identifying additional novel cellular targets for these new therapies.

With detailed methods and protocols for the identification and assay of these targets, "New Antibiotic Targets" provides laboratory investigators with the vital tools they need to test the antimicrobial potential of products and to curb the rise of so many infectious diseases.

Keywords

antibiotic therapy antibiotics antimicrobial antimicrobial peptides assay bacteria drug targets infection infections infectious infectious disease infectious diseases

Editors and affiliations

  • W. Scott Champney
    • 1
  1. 1.Department of Biochemistry and Molecular BiologyEast Tennessee State UniversityJohnson

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59745-246-5
  • Copyright Information Humana Press 2008
  • Publisher Name Humana Press
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-58829-915-4
  • Online ISBN 978-1-59745-246-5
  • Series Print ISSN 1543-1894
  • Series Online ISSN 1940-6037
  • About this book