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Lupus

Molecular and Cellular Pathogenesis

  • Gary M. Kammer
  • George C. Tsokos

Part of the Contemporary Immunology book series (CONTIM)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Evelyn V. Hess
    Pages 1-12
  3. Bruce N. Cronstein, Allison Reiss, Sandeep Malhotra
    Pages 13-20
  4. H. Michael Belmont, Ashok R. Amin, Steven B. Abramson
    Pages 21-42
  5. Rebecca S. Tuetken, Ae-Kyung Yi, Arthur M. Krieg
    Pages 79-100
  6. Pércio S. Gulko, Robert J. Winchester
    Pages 101-123
  7. Chandra Mohan, Laurence Morel, Edward K. Wakeland
    Pages 124-139
  8. Andrei Shustov, Violetta Rus, Phuong Nguyen, Charles S. Via
    Pages 140-151
  9. Stanford L. Peng, Joe Craft
    Pages 152-166
  10. Stamatis-Nick C. Liossis, George C. Tsokos
    Pages 167-180
  11. Mark J. Mamula
    Pages 202-219
  12. Jeannine M. Scott, Bruce C. Richardson
    Pages 278-298
  13. David A. Horwitz, J. Dixon Gray, Katzuo Ohtsuka, Bricia Toro, Mary M. Stimmler, Lillie Hsu
    Pages 312-320
  14. Barry S. Handwerger, Irina Luzina, Ludmila da Silva, Catherine E. Storrer, Charles S. Via
    Pages 321-340
  15. Motoko Honda, Mariana Linker-Israeli
    Pages 341-360
  16. Daniela Verthelyi, Dennis M. Klinman
    Pages 361-370
  17. Bevra H. Hahn, Fanny M. Ebling, Betty P. Tsao, Ram R. Singh
    Pages 371-388
  18. Minoru Satoh, Hanno B. Richards, Westley H. Reeves
    Pages 399-416
  19. David S. Pisetsky
    Pages 417-428
  20. Jeff Newman, Betty Diamond
    Pages 429-447
  21. Robert A. S. Roubey
    Pages 471-491
  22. Jill P. Buyon
    Pages 492-513
  23. John P. Atkinson, Jürg A. Schifferli
    Pages 529-540
  24. Daniel J. Birmingham
    Pages 541-556
  25. Andrew W. Gibson, Jianming Wu, Jeffrey C. Edberg, Robert P. Kimberly
    Pages 557-573
  26. Mark H. Wener
    Pages 574-598
  27. Robert B. Zurier
    Pages 599-611
  28. W. Joseph McCune, David A. Fox
    Pages 612-641
  29. Mark J. Halvorson, William C. Gause
    Pages 656-670
  30. Hui-Chen Hsu, Huang-Ge Zhang, Tong Zhou, John D. Mountz
    Pages 671-693
  31. Back Matter
    Pages 695-709

About this book

Introduction

Leading basic and clinical investigators from around the world summarize the most recent research on the molecular and cellular origins of lupus. Their cutting-edge articles review the mechanisms underlying abnormal immunity and introduce the powerful new concept that a disorder of multiple genes underlies the abnormal immune response, leading directly to the development of lupus. This pathophysiology is shown to involve a wide variety of cell types, including T cells, B cells, natural killer cells, macrophages/monocytes, and endothelial cells. Over time, the resulting long-term inflammation causes irreversible cell destruction and, ultimately, organ failure. Lupus: Molecular and Cellular Pathogenesis is a masterful new synthesis of all the new knowledge emerging today about lupus. Its new perspectives will sharpen the focus of research and ultimately lead to better and more effective treatment.

Keywords

Antigen apoptosis autoimmunity bacteria cytokine genetics inflammation lymphocytes macrophages pathogenesis pathophysiology physiology therapy thrombosis

Editors and affiliations

  • Gary M. Kammer
    • 1
  • George C. Tsokos
    • 2
    • 3
  1. 1.Section on Rheumatology, Department of Internal MedicineThe Wake Forest University School of MedicineWinston-SalemUSA
  2. 2.Division of Rheumatology and ImmunologyUniformed Services University of Health SciencesBethesdaUSA
  3. 3.Department of Clinical PhysiologyWalter Reed Army Institute of ResearchUSA

Bibliographic information