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Chemokines and Cancer

  • Barrett J. Rollins

Part of the Contemporary Cancer Research book series (CCR)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Chemokine Physiology

    1. Front Matter
      Pages 1-1
    2. Steven L. Kunkel, Nicholas W. Lukacs, Robert M. Strieter, Theodore Standiford, Stephen W. Chensue
      Pages 3-19
  3. Tumor Infiltration by Leukocytes

    1. Front Matter
      Pages 33-33
    2. Alberto Mantovani, Annunciata Vecchi, Silvano Sozzani, Antonio Sica, Paola Allavena
      Pages 35-49
    3. Ghislain Opdenakker, Jo Van Damme
      Pages 51-69
  4. Modulation of Host Responses to Cancer

    1. Front Matter
      Pages 71-71
    2. Dennis D. Taub
      Pages 73-93
    3. Barrett J. Rollins, Howard A. Fine, Long Gu, Kenzo Soejima, Susan Tseng
      Pages 95-113
    4. Thomas A. Hamilton, Charles S. Tannenbaum, James Finke, Ronald Bukowski
      Pages 115-126
  5. Chemokines and Tumor Growth, Metastasis, and Angiogenesis

    1. Front Matter
      Pages 127-127
    2. Ji Ming Wang, Weipin Shen, Oleg Chertov, Jo Van Damme, Joost J. Oppenheim
      Pages 129-141
    3. Robert M. Strieter, Bruno DiGiovine, Peter J. Polverini, Steven L. Kunkel, Armen Shanafelt, Joseph Hesselgesser et al.
      Pages 143-167
    4. Ann Richmond, Hamid Haghnegahdar, Rebecca Shattuck-Brandt, Lauren D. Wood, Chaitanya S. Nirodi, James D. Owen et al.
      Pages 169-189
  6. Chemokines and Specific Malignancies

    1. Front Matter
      Pages 191-191
    2. Rupert P. M. Negus, Frances R. Balkwill
      Pages 193-205
    3. Frank Rösl, Kerstin Kleine-Lowinski, Harald zur Hausen
      Pages 207-225
    4. Teizo Yoshimura, Jun-ichi Kuratsu
      Pages 227-241
    5. Jean E. Crabtree, Ivan J. D. Lindley
      Pages 243-259
  7. Chemokines and Stem Cell Proliferation

    1. Front Matter
      Pages 261-261
    2. Hal E. Broxmeyer, Chang H. Kim
      Pages 263-291
    3. Gerard J. Graham, Robert J. B. Nibbs
      Pages 293-310
  8. Back Matter
    Pages 311-321

About this book

Introduction

Chemokines and Cancer synthesizes a state-of-the-art understanding of the role that chemokines and their receptors play in the pathophysiology of malignancy. It examines the influence of chemokines on a broad array of malignant cells, including their effects on such intrinsic properties as growth and movement, as well as exploring their influence on the host's response to a growing tumor. The authors also demonstrate the physiological consequences of chemokine expression and suggest how chemokines can be used to regulate tumor growth in vivo, including their direct effects on tumor growth, on tumor destruction by host inflammatory cells, and on tumor angiogenesis. The only book available that relates chemokines to cancer, Chemokines and Cancer holds out the promise of novel therapeutic approaches to malignancy through the manipulation of chemokines and/or their receptors.

Keywords

angiogenesis carcinogenesis cell cytokines melanoma metastasis stem cell tumor tumor growth tumorigenesis

Editors and affiliations

  • Barrett J. Rollins
    • 1
  1. 1.Department of Adult Oncology, Dana-Farber Cancer InstituteBostonUSA

Bibliographic information