Endocrinology of Breast Cancer

  • Andrea Manni

Part of the Contemporary Endocrinology book series (COE, volume 11)

Table of contents

  1. Front Matter
    Pages i-x
  2. Hormonal Control of Mammary Development and Growth

    1. Front Matter
      Pages 1-1
    2. Richard E. Blackwell, Karen R. Hammond
      Pages 3-20
    3. Geneviève Plu-Bureau, Philippe Touraine, Pierre Mauvais-Jarvis
      Pages 21-37
  3. Carcinogenesis

    1. Front Matter
      Pages 53-53
    2. Heather Spencer Feigelson, Brian E. Henderson
      Pages 55-67
    3. Rajeshwar Rao Tekmal, Richard J. Santen
      Pages 79-92
    4. Maria Luisa Veronese, Florencia Bullrich, Carlo M. Croce
      Pages 93-108
    5. Luigi Dogliotti, Pasquale Caraci
      Pages 109-116
  4. Tumor Progression

    1. Front Matter
      Pages 117-117
    2. Richard J. Pietras, Mark D. Pegram
      Pages 133-153
    3. Kevin J. Cullen, Sahana S. Kaup, Audrey A. Rasmussen
      Pages 155-168
    4. Jan G. M. Klijn, Els M. J. J. Berns, John A. Foekens
      Pages 205-220
  5. Estrogen, Progestins, and Prolactin in Breast Cancer Biology: Targets for Treatment

    1. Front Matter
      Pages 231-231

About this book


In Endocrinology of Breast Cancer, Andrea Manni, MD, organizes a cutting-edge review of how derangements in the hormonal and growth factor mechanisms controlling normal mammary development lead to breast cancer. Drawing on the multidisciplinary expertise of leading authorities, the book highlights the roles of oncogenes and tumor suppressor genes, spelling out the importance of autocrine/paracrine loops (e.g., stromal epithelial interactions) in supporting breast cancer cell proliferation and the progression to hormone independence. The book's many prominent contributors also illuminate significant recent advances in the biochemistry and physiology of hormone receptors and review the state-of -the-art in the endocrine therapy of breast cancer.
Providing a unique, integrated overview of the most significant developments involving the hormonal aspects of breast cancer, Endocrinology of Breast Cancer constitutes an invaluable, broad-ranging resource for all basic scientists, clinicians, and fellows-in-training who want to better understand and treat this most common malignancy.


Carcinom G proteins classification growth factor hormone receptors insulin-like prolactin

Editors and affiliations

  • Andrea Manni
    • 1
  1. 1.College of MedicineThe Pennsylvania State UniversityHersheyUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59259-699-7
  • Copyright Information Humana Press 1999
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4757-5139-0
  • Online ISBN 978-1-59259-699-7
  • About this book