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Chemoradiation in Cancer Therapy

  • Hak Choy

Part of the Cancer Drug Discovery and Development book series (CDD&D)

Table of contents

  1. Front Matter
    Pages i-xii
  2. General/Background

    1. Front Matter
      Pages 1-1
    2. Hak Choy, Robert M. MacRae
      Pages 3-22
    3. Muhammad Wasif Saif, Robert B. Diasio
      Pages 23-44
  3. Mechanisms of Interaction of Specific Chemotherapeutic Agents with Radiation

    1. Front Matter
      Pages 45-45
    2. Robert M. MacRae, Hak Choy
      Pages 65-91
    3. Tyvin A. Rich
      Pages 93-103
    4. Jerome Landry, William Blackstock, Robert M. MacRae, Gary Yang, Hak Choy
      Pages 105-126
  4. Clinical Applications

    1. Front Matter
      Pages 127-127
    2. Heather A. Curry, Walter J. Curran Jr.
      Pages 129-144
    3. Julie R. Brahmer, Larry Kleinberg, David S. Ettinger
      Pages 197-213
    4. Arlene Forastiere, Bapsi Chak
      Pages 215-235
    5. Silvia C. Formenti, Matthew Volm
      Pages 237-251
    6. Jason H. Lee, Christopher G. Willett
      Pages 271-289
  5. Specific Molecular Targeted Agents

    1. Front Matter
      Pages 321-321
    2. Stacy L. Moulder, Carlos L. Arteaga
      Pages 339-348
    3. Stephen G. Swisher, Jack A. Roth
      Pages 349-358
    4. Dennis E. Hallahan, Don Stacy
      Pages 359-378
    5. Jeffrey S. Humphrey, Karen Price, Elora Gupta, Andrew Baxter, John Bird, Daryl Sonnichsen et al.
      Pages 379-390
    6. Hong Pyo, Raymond N. DuBois, Hak Choy
      Pages 391-408
  6. Back Matter
    Pages 409-420

About this book

Introduction

The combination of chemotherapeutic drugs and radiation to treat solid tumors has now become a common treatment option in many clinical settings. In Chemoradiation in Cancer Therapy, internationally recognized experts in cancer biology and clinical research review the present status of these multimodality approaches to the management of solid tumors and speculate on possible future strategies for their use. As part of their comprehensive survey, the authors detail applications of combined modality therapy in lung, esophageal, breast, gastric, pancreatic, colon, and rectal cancers. They also show how radiation interacts with such chemotherapeutic agents as the platinum complexes, taxanes, and gemcitabine in the treatment of malignant gliomas, and head and neck cancer. Rounding out the presentation is a review of how to integrate new specific molecular-targeted agents into future multimodality therapy. Here the discussion centers on the antibody for the epidermal growth factor receptor (EGFR), antiangiogenesis agents, farnesyltransferase inhibitors (FTIs), gene therapies, and signaling pathway inhibitors in combination with radiotherapy, and with or without classical chemotherapeutic agents.
State-of-the-art and forward-looking, Chemoradiation in Cancer Therapy offers oncologists a thorough understanding of today's best current and future strategies available for the treatment of solid tumors by chemoradiation therapy.

Keywords

breast cancer cancer carcinoma chemotherapy gene therapy radiation radiotherapy tumor

Editors and affiliations

  • Hak Choy
    • 1
  1. 1.Department of Radiation OncologyVanderbilt University Medical CenterNashvilleUSA

Bibliographic information