Neurobiology of Spinal Cord Injury

  • Robert G. Kalb
  • Stephen M. Strittmatter

Part of the Contemporary Neuroscience book series (CNEURO)

Table of contents

  1. Front Matter
    Pages i-xvii
  2. Gordon K. T. Chu, Charles H. Tator, Michael Tymianski
    Pages 23-55
  3. Serge Rossignol, Marc Bélanger, Connie Chau, Nathalie Giroux, Edna Brustein, Laurent Bouyer et al.
    Pages 57-87
  4. John D. Steeves, Wolfram Tetzlaff
    Pages 113-129
  5. Li-Hsien Wang, Alyson Fournier, Fumio Nakamura, Takuya Takahashi, Robert G. Kalb, Stephen M. Strittmatter
    Pages 131-153
  6. Juan C. Bartolomei, Charles A. Greer
    Pages 195-213
  7. Back Matter
    Pages 277-284

About this book

Introduction

In Neurobiology of Spinal Cord Injury, a panel of distinguished researchers review the latest scientific understanding of spinal cord injury (SCI), focusing on the mechanisms causing paralysis after spinal cord trauma, the molecular determinants of neural regeneration, and methods for improving function after damage. The authors examine the role of intracellular Ca2+ in neuronal death, the possibility of spinal learning, growth-promoting molecules for regenerating neurons, and the biochemistry and cell biology of microtubules. Among the treatment possibilities discussed are cell transplantation strategies, including the use of fetal spinal cord tissue, remyelination in spinal cord demyelination models, high dose steroid therapy immediately after SCI, and the mixed use of anti- and proinflammatories. Emphasis is given to cell transplantation as a potential means to improve function. Comprehensive and highly promising, Neurobiology of Spinal Cord Injury summarizes the great progress that has been made in understanding and combating the paralysis that follows spinal cord injury, delineating today's major therapeutic interventions for alleviating the neurological deficits of the spinally injured.

Keywords

biochemistry biology neurobiology neurons spinal cord trauma

Editors and affiliations

  • Robert G. Kalb
    • 1
  • Stephen M. Strittmatter
    • 2
  1. 1.Departments of Neurology and PharmacologyYale University School of MedicineNew HavenUSA
  2. 2.Department of NeurologyYale University School of MedicineNew HavenUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-59259-200-5
  • Copyright Information Humana Press 2000
  • Publisher Name Humana Press, Totowa, NJ
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-61737-126-4
  • Online ISBN 978-1-59259-200-5
  • About this book