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Pathogen Genomics

Impact on Human Health

  • Karen Joy Shaw

Part of the Infectious Disease book series (ID)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Viruses

    1. Front Matter
      Pages xvii-xvii
    2. Klaus Früh, Peter Ghazal
      Pages 1-11
    3. Steffney Elise Rought, Roman Sasik, Davey Mitchell Smith, Jacques Corbeil
      Pages 13-24
    4. Yijan Elaine Chang, Laimonis A. Laimins
      Pages 25-38
    5. Gregory C. Fanning, Janet L. Macpherson, Geoff Symonds
      Pages 39-51
  3. Bacteria

    1. Front Matter
      Pages N1-N1
    2. Marcel A. Behr, Stephen V. Gordon
      Pages 69-81
    3. Michael J. Pucci, John F. Barrett, Thomas J. Dougherty
      Pages 83-96
    4. Brian J. Morrow, Karen Joy Shaw
      Pages 97-112
    5. Alireza Shamaei-Tousi, Sven Bergström
      Pages 133-154
  4. Fungi

    1. Front Matter
      Pages N3-N3
    2. Beth DiDomenico, Scott S. Walker
      Pages 155-166
    3. Marianne D. De Backer, Walter H. M. L. Luyten, Hugo F. Vanden Bossche
      Pages 167-196
    4. Jennifer K. Lodge, John R. Perfect
      Pages 197-214
    5. Rosanna Pena-Muralla, Patricia Ayoubi, Marcia Graminha, Nilce M. Martinez-Rossi, Antonio Rossi, Rolf A. Prade
      Pages 215-230
    6. Glenmore Shearer Jr.
      Pages 231-245
    7. Theo N. Kirkland, Garry T. Cole
      Pages 247-254
  5. Protozoa

    1. Front Matter
      Pages N5-N5
    2. Jessica C. Kissinger, Michael J. Crawford, David S. Roos, James W. Ajioka
      Pages 255-279
    3. Barbara J. Mann, Brendan J. Loftus
      Pages 281-302
  6. Back Matter
    Pages 303-309

About this book

Introduction

Genome sequencing and analysis have yielded a rich harvest of fundamental information about pathogenesis and have raised significant new possibilities for effective therapeutic intervention. In Pathogen Genomics: Impact on Human Health, a panel of leading infectious disease researchers and pharmaceutical scientists comprehensively review the latest genomic technologies and their application to infectious disease prevention, diagnosis, and treatment. The authors' cross-disciplinary approach-with expertise acquired from studying disease-causing viruses, bacteria, fungi, and protozoa-reveals how sequence information from diverse pathogens has uncovered novel targets for drug discovery, antigenic determinants for vaccine development, as well as diagnostic tools. The authors also discuss the application of DNA microarrays and the impact of genome sequencing comparisons to the discovery and choices of novel drug targets. The result is a better understanding of how these tools can be used to explore the fundamentals of microbial pathogenesis, as well as how pathogens interact with each other and with their host environments.
Broad-ranging and illuminating, Pathogen Genomics: Impact on Human Health offers today's infectious disease specialists an authoritative analysis of the new genomic technologies and their productive application to drug discovery, vaccine development, and diagnostics.

Keywords

AIDS Antigen HIV antiviral drug bacteria infectious infectious disease vaccine

Editors and affiliations

  • Karen Joy Shaw
    • 1
  1. 1.Department of Infectious Diseases, Johnson and Johnson Pharmaceutical Research and DevelopmentL. L. C.San DiegoUSA

Bibliographic information