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Endocrinology of the Lung

Development and Surfactant Synthesis

  • Carole R. Mendelson

Part of the Contemporary Endocrinology book series (COE)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Alan H. Jobe, Machiko Ikegami
    Pages 45-57
  3. Carole R. Mendelson, Laura F. Michael, Pampee P. Young, Jinxing Li, Joseph L. Alcorn
    Pages 59-80
  4. Tina Jaskoll, Michael Melnick
    Pages 105-124
  5. Maria Venihaki, Louis J. Muglia, Joseph A. Majzoub
    Pages 125-140
  6. Heber C. Nielsen, John S. Torday
    Pages 141-159
  7. Richard D. Zachman, Mary A. Grummet
    Pages 161-179
  8. Jeanne M. Snyder, Thomas N. George, Olga L. Miakotina
    Pages 181-200
  9. Wayne A. Price, Alan D. Stiles
    Pages 201-224
  10. Nicholas J. Cartel, Martin Post
    Pages 225-240
  11. Lewis P. Rubin, John S. Torday
    Pages 269-297
  12. Mary E. Sunday, Ernest Cutz
    Pages 299-336
  13. Back Matter
    Pages 337-344

About this book

Introduction

During the past thirty years, great progress has been made in defining the roles of steroid, peptide, and polypeptide hormones in the processes of lung morphogenesis, differentiation of specialized cell types, and surfactant synthesis. In Endocrinology of the Lung, Carole Mendelson has assembled a panel of leading investigators to critically review the roles of various classes of endocrine, paracrine, and neuroendocrine factors in the regulation of lung development and surfactant production. Special attention is accorded the actions of glucocorticoids in lung branching morphogenesis and the synthesis of surfactant glycerophospholipids and proteins. Also extensively examined are the roles of cell-cell interactions and the elaboration of various growth factors and bioactive peptides in pulmonary cell differentiation, gene expression, and pathophysiology. The model systems utilized in these studies range from whole animal to transgenic and gene-targeted mice, to organ and cell culture. State-of-the-art and comprehensive, Endocrinology of the Lung constitutes a powerful new standard guide that illuminates the complex endocrinology of the lung for investigators actively studying hormone action in pulmonary biology and medicine today.

Keywords

glucocorticoid growth factor insulin insulin-like receptor signaling thyroid hormone

Editors and affiliations

  • Carole R. Mendelson
    • 1
  1. 1.Department of Biochemistry and Obstetrics-GynecologyUniversity of Texas Southwestern Medical Center at DallasDallasUSA

Bibliographic information