Suicide Gene Therapy

Methods and Protocols

  • Nejat Düzgüneş

Part of the Methods in Molecular Biology book series (MIMB, volume 1895)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Nejat Düzgüneş
    Pages 1-9
  3. Jubayer A. Hossain, Kristoffer Riecken, Hrvoje Miletic, Boris Fehse
    Pages 11-26
  4. Wan-Chi Hsiao, Shian-Ying Sung, Leland W. K. Chung, Chia-Ling Hsieh
    Pages 27-42
  5. Henrique Faneca, Nejat Düzgüneş, Maria C. Pedroso de Lima
    Pages 43-55
  6. Cestmir Altaner, Ursula Altanerova
    Pages 75-85
  7. Erdogan Pekcan Erkan, Nurten Saydam, Clark C. Chen, Okay Saydam
    Pages 87-96
  8. Bryan Holvoet, Cindy Leten, Christophe M. Deroose, Uwe Himmelreich
    Pages 123-134
  9. Chung-Ho Sun, Kristian Berg, Henry Hirschberg
    Pages 165-176
  10. Nejat Düzgüneş, Jennifer Cheung, Krystyna Konopka
    Pages 177-184
  11. Back Matter
    Pages 185-190

About this book


This detailed volume explores the methods used for most of the recent approaches to suicide gene therapy of cancer, which exploits promoters that are specific to cancer cells, thereby ensuring (or greatly increasing the likelihood) that the therapeutic gene is expressed only in cancer cells. The book also contains chapters describing methods to improve the safety of cell therapy and techniques utilizing bone marrow mesenchymal cells. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.  

Authoritative and practical, Suicide Gene Therapy: Methods and Protocols serves as an ideal guide for researchers expanding upon our knowledge and application of this vital form of cancer therapy.


Cancer treatment Therapeutic genes Tumors Cell therapy Bone marrow mesenchymal cells

Editors and affiliations

  • Nejat Düzgüneş
    • 1
  1. 1.Department of Biomedical Sciences, Arthur A. Dugoni School of DentistryUniversity of the PacificSan FranciscoUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, LLC, part of Springer Nature 2019
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-8921-8
  • Online ISBN 978-1-4939-8922-5
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site