Overview
- Provides a comprehensive review of PKD mutations, pathophysiologic mechanisms of PKD, renal and extrarenal manifestations of PKD, clinical trials and emerging therapies in PKD, and appropriate management of patients with PKD
- Written by top professionals in the field
- Well-illustrated resource serves both clinician and researcher
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About this book
This comprehensive guide to polycystic kidney disease captures the growing knowledge of this common, potentially-fatal and hereditary disease. The first two sections of the book provide an overview of PKD gene structures, mutations and pathophysiologic mechanisms. This is followed by chapters focused on PKD’s clinical features, including renal and extrarenal manifestations, and appropriate management of patients. The final section covers current clinical trials and emerging therapies in PKD. Authored by experts in the field, this book provides the clinician and researcher with critical information on basic and translational science and clinical approaches in one concise resource.
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Keywords
Table of contents (15 chapters)
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Front Matter
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PKD: Mechanisms of Disease
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Front Matter
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ADPKD: Clinical Features
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Front Matter
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ADPKD: Clinical Trials and Emerging Therapies
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Front Matter
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Editors and Affiliations
About the editors
John J. Bissler, MD
Federal Express Chair of Excellence, Professor and Chief, Division of Nephrology, Department of Pediatrics, Director of the Tuberous Sclerosis Center of Excellence at Le Bonheur Children’s Hospital, Medical Director of Nephrology, St. Jude Children's Research Hospital, University of Tennessee Health Science Center
University of Tennessee Health Science Center
Children’s Foundation Research Center
Memphis, TN
Benjamin D. Cowley, Jr., M.D., F.A.C.P., F.A.S.N.
Professor of Medicine
Chief, Nephrology & Hypertension
John Gammill Professor in Polycystic Kidney Disease
University of Oklahoma Health Sciences Center
Oklahoma City, OK
Bibliographic Information
Book Title: Polycystic Kidney Disease
Book Subtitle: Translating Mechanisms into Therapy
Editors: Benjamin D. Cowley, Jr., John J. Bissler
DOI: https://doi.org/10.1007/978-1-4939-7784-0
Publisher: Springer New York, NY
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2018
Hardcover ISBN: 978-1-4939-7782-6Published: 25 May 2018
Softcover ISBN: 978-1-4939-9284-3Published: 25 July 2019
eBook ISBN: 978-1-4939-7784-0Published: 24 May 2018
Edition Number: 1
Number of Pages: XIII, 273
Number of Illustrations: 20 b/w illustrations, 42 illustrations in colour
Topics: Nephrology