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NMDA Receptors

Methods and Protocols

  • Nail Burnashev
  • Pierre Szepetowski

Part of the Methods in Molecular Biology book series (MIMB, volume 1677)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Kasper B. Hansen, Feng Yi, Riley E. Perszyk, Frank S. Menniti, Stephen F. Traynelis
    Pages 1-80
  3. NMDAR Subunits Expression and Mutations

    1. Front Matter
      Pages 81-81
    2. Todd D. Prickett, Jared J. Gartner, Yardena Samuels
      Pages 93-116
    3. Matteo Gastaldi, Patrick Waters, Angela Vincent
      Pages 117-126
  4. Studying Structure–Function Relations in NMDARs

    1. Front Matter
      Pages 127-127
    2. Katie F. M. Marwick, Giles E. Hardingham
      Pages 137-144
    3. Feng Yi, Stephen F. Traynelis, Kasper B. Hansen
      Pages 145-162
    4. Cécile Perrio, Olivier Nicole, Alain Buisson
      Pages 171-183
  5. Analysis of NMDAR Function/Activity

    1. Front Matter
      Pages 199-199
    2. Rolf Sprengel, Ahmed Eltokhi, Frank N. Single
      Pages 201-230
    3. Alexandre Pons-Bennaceur, Natalia Lozovaya
      Pages 231-239
    4. Stéphane Peineau, Vincent Degos, Catherine Verney, Pierre Gressens
      Pages 253-263
    5. Asya Makhro, Lars Kaestner, Anna Bogdanova
      Pages 265-282
    6. Roustem Khazipov
      Pages 283-290
    7. A. Florence Keller, Jean-Marie C. Bouteiller, Theodore W. Berger
      Pages 291-306
  6. Back Matter
    Pages 307-314

About this book

Introduction

This volume explores the latest techniques used by researchers to help them better understand the NMDAR structure-function relations, principles, and rules that govern how NMDARs operate in brain processing. The volume includes a detailed introductory chapter describing the field and is divided into three parts. Topics covered in the volume include: quantification of NMDAR subunit genes expression by qRT-PCR; detection of NMDARs antibodies in encephalitis; recombinant channels in host cells using a fast agonist application system; GluNs detection and functions in microglial cells; and NMDARs as voltage sensors. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and practical, NMDA Receptors: Methods and Protocols is a valuable resource that discusses the diversity of the currently-used methods, the importance of NMDARs and their complexity, and the progress that has already been made. This book will be of interest to scientists, clinicians, and industry professionals working in this field.

Keywords

NMDARs plasticity epilepsy CNS encephalitis high-resolution live imaging

Editors and affiliations

  • Nail Burnashev
    • 1
  • Pierre Szepetowski
    • 2
  1. 1.Mediterranean Institute of Neurobiology (INMED)Aix-Marseille University, INSERM U901MarseilleFrance
  2. 2.Mediterranean Institute of Neurobiology (INMED)Aix-Marseille University, INSERM U901MarseilleFrance

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-7321-7
  • Copyright Information Springer Science+Business Media LLC 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-7320-0
  • Online ISBN 978-1-4939-7321-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site