Current Proteomic Approaches Applied to Brain Function

  • Enrique Santamaría
  • Joaquín Fernández-Irigoyen

Part of the Neuromethods book series (NM, volume 127)

Table of contents

  1. Subcellular Neuroproteomics

    1. Matías Sáenz-Cuesta, Enrique Santamaría, Joaquin Fernández-Irigoyen, David Otaegui
      Pages 245-253
    2. Aline G. Santana, Giuliana S. Zuccoli, Verônica M. Saia-Cereda, Juliana S. Cassoli, Daniel Martins-de-Souza
      Pages 281-288
  2. Bioinformatics

    1. Front Matter
      Pages 303-303
    2. Julian Uskoreit, Maike Ahrens, Katalin Barkovits, Katrin Marcus, Martin Eisenacher
      Pages 305-324
    3. Ravi Sirdeshmukh, Savita Jayaram, Manoj Kumar Gupta, Pranali Sonpatki, Manika Singh, Raksha A. Ganesh et al.
      Pages 325-356
  3. Back Matter
    Pages 357-360

About this book

Introduction

This volume focuses on protein analysis covering a wide spectrum of the utility of mass spectrometry within neurobiological disciplines. The chapters in this book discuss label (iTRAQ, TMT, protein arrays) and label-free workflows (SWATH, MALDI Imaging, and label-free quantitation). Other chapters look at experimental strategies targeted to the identification and quantitation of specific lipids and post-translational modifications, as well as proteomic workflows that focus on characterization of subcellular proteomes. The last few chapters in the book describe various bioinformatics pipelines used to analyze the molecular data derived from high-throughput transcriptomic and proteomic experiments on brain tissue. The Neuromethods series offers chapters with key advice and procedure specifics to empower the readers to successfully achieve their own scientific and experimental goals.

Thorough and comprehensive, Current Proteomic Approaches Applied to Brain Function is a valuable resource for graduate students and postdoctoral fellows interested in neuroproteomics, as well as researchers looking for further insight into the growing field of mass spectrometry in neuroscience.


Keywords

mass spectrometry neurodegenerative disease fluorescence activated nuclei sorting glycoproteomics neuroblastoma phosphoproteome FANS

Editors and affiliations

  • Enrique Santamaría
    • 1
  • Joaquín Fernández-Irigoyen
    • 2
  1. 1.Clinical Neuroproteomics Unit, Navarrabiomed, Navarra Health DepartmentPublic University of Navarra, Proteored-Institute of Health Carlos III (ISCIII), Navarra Institute for Health Research (IdiSNA)PamplonaSpain
  2. 2.Clinical Neuroproteomics Unit, Navarrabiomed, Navarra Health DepartmentPublic University of Navarra, Proteored-Institute of Health Carlos III (ISCIII), Navarra Institute for Health Research (IdiSNA)PamplonaSpain

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-7119-0
  • Copyright Information Springer Science+Business Media LLC 2017
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-7118-3
  • Online ISBN 978-1-4939-7119-0
  • Series Print ISSN 0893-2336
  • Series Online ISSN 1940-6045
  • About this book