Multipotent Stem Cells of the Hair Follicle

Methods and Protocols

  • Robert M Hoffman

Part of the Methods in Molecular Biology book series (MIMB, volume 1453)

Table of contents

  1. Front Matter
    Pages i-xi
  2. John Mignone, Natalia Peunova, Grigori Enikolopov
    Pages 7-14
  3. Lingna Li, Robert M. Hoffman
    Pages 15-20
  4. Sumiyuki Mii, Jennifer Duong, Yasunori Tome, Aisada Uchugonova, Fang Liu, Yasuyuki Amoh et al.
    Pages 39-47
  5. Ying Zheng, Jen-Chih Hsieh, Julia Escandon, George Cotsarelis
    Pages 57-69
  6. Katsunari Tezuka, Koh-ei Toyoshima, Takashi Tsuji
    Pages 71-84
  7. Eduardo Martínez-Martínez, Eileen Uribe-Querol, Claudio I. Galván-Hernández, Gabriel Gutiérrez-Ospina
    Pages 93-107
  8. Wenluo Cao, Fang Liu, Yasuyuki Amoh, Robert M. Hoffman
    Pages 137-144
  9. Masateru Yashiro, Sumiyuki Mii, Ryoichi Aki, Yuko Hamada, Nobuko Arakawa, Katsumasa Kawahara et al.
    Pages 151-159
  10. Satoshi Kajiura, Sumiyuki Mii, Ryoichi Aki, Yuko Hamada, Nobuko Arakawa, Katsumasa Kawahara et al.
    Pages 173-178
  11. Back Matter
    Pages 179-180

About this book


This volume discusses methods for the study of multipotent and pluripotent stem cells of the hair follicle. The stem cells described are involved in both the growth of the hair follicle and its production of the hair shaft, as well as the growth of the hair follicle sensory nerve. Multipotent Stem Cells of the Hair Follicle: Methods and Protocols also explores very unexpected results such as that of the hair follicle-associated-pluripotent (HAP) stem cells, which not only have the capability for regenerating the hair follicle sensory nerve, but also can differentiate ex vivo and in vivo to multiple cell types not associated with the hair follicle—these include glial cells, motor neurons, and beating cardiac muscle cells. The potential for HAP stem cells for regenerative medicine is also discussed in detail. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Multipotent Stem Cells of the Hair Follicle: Methods and Protocols is a valuable resource for researchers interested in this field.



pluripotent stem cells hair follicle sensory nerve hair follicle-associated-pluripotent (HAP) stem cells glial cells motor neurons cardiac muscle cells regenerative medicine

Editors and affiliations

  • Robert M Hoffman
    • 1
  1. 1.University of CaliforniaAntiCancer, Inc.San DiegoUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3784-4
  • Online ISBN 978-1-4939-3786-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site