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Circadian Clocks: Role in Health and Disease

  • Book
  • © 2016

Overview

Editors:
  1. Michelle L. Gumz

    1. University of Florida, Gainesville, USA

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  • Updates readers on new findings concerning the essential role of biological rhythms
  • Addresses both basic research and clinical aspects
  • Written by leading scientists and clinicians

Part of the book series: Physiology in Health and Disease (PIHD)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-vi
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  2. Introduction to Circadian Rhythms and Mechanisms of Circadian Oscillations

    • David R. Weaver
    Pages 1-55

  3. The Circadian Timing System and Endocrine Physiology

    • Michael T. Sellix
    Pages 57-102

  4. Circadian Regulation of Sleep

    • Kazuo Mishima
    Pages 103-115

  5. The Human SCN in Health and Neuropsychiatric Disorders: Postmortem Observations

    • Ai-Min Bao, Dick F. Swaab
    Pages 117-152

  6. Mammalian Circadian Clocks and Metabolism: Navigating Nutritional Challenges in a Rhythmic World

    • Jeremy J. Stubblefield, Carla B. Green
    Pages 153-174

  7. Circadian Regulation of Renal Function

    • Kristen Solocinski, Gianluigi Mazzoccoli, Michelle L. Gumz
    Pages 175-198

  8. Circadian Rhythms and the Circadian Clock in the Cardiovascular System

    • R. Daniel Rudic
    Pages 199-224

  9. The Cardiac Clock

    • Faisal J. Alibhai, Elena V. Tsimakouridze, Cristine J. Reitz, W. Glen Pyle, Tami A. Martino
    Pages 225-250

  10. Regulation of Immunity by the Circadian Clock

    • Alba de Juan, David Druzd, Louise Ince, Christoph Scheiermann
    Pages 251-266

  11. Rhythms in the Digestive System

    • David B. Rhoads, Lynne L. Levitsky, Ali Tavakkoli
    Pages 267-293

  12. Chronotherapy of Blood Pressure Medications to Improve Management of Hypertension and Reduce Vascular Risk

    • Ramón C. Hermida, Diana E. Ayala, Michael H. Smolensky, Francesco Portaluppi
    Pages 295-334

  13. The Circadian Clock as a Drug Target

    • Sadichha Situala, Ariadna Amador, Thomas P. Burris
    Pages 335-366

  14. Back Matter

    Pages 367-378
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Keywords

About this book

This book sheds new light on the molecular mechanisms that generate circadian rhythms. It examines how biological rhythms influence physiological processes such as sleep, hormone synthesis and secretion, immunity, kidney function, the cardiovascular system, blood pressure, and the digestive system. Clinical implications are considered while exploring the impact of rhythms on neuropsychiatric disorders and chronotherapy’s potential for reducing cardiovascular risk. Offering a cross-section of expertise in both basic and translational (bench-to-bedside) research, this book serves as a guide for physicians and scientists who wish to learn more about the impact of circadian rhythms on physiological processes in health and disease. 

Reviews

“The audience is scientists or students interested in the role circadian clocks play in modulating the functions of physiological systems. … This is a high quality, comprehensive treatment of a very complex field of physiology. It is written in a logical, understandable manner that makes it easier to comprehend difficult topics. … Doctoral students in physiology will find their understanding of homeostasis and human survival enhanced by this book. It is an excellent contribution to the field of physiology.” (David R. Bell, Doody's Book Reviews, August, 2016)

Editors and Affiliations

  • University of Florida, Gainesville, USA

    Michelle L. Gumz

About the editor

Michelle L. Gumz, Ph.D., Assistant Professor, University of Florida, Department of Medicine, Division of Nephrology, Hypertension and Renal Transplantation, Gainesville FL, USA

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