Vaccine Design

Methods and Protocols: Volume 1: Vaccines for Human Diseases

  • Sunil Thomas

Part of the Methods in Molecular Biology book series (MIMB, volume 1403)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Vaccines: Introduction

    1. Front Matter
      Pages 1-1
    2. Puja H. Nambiar, Alejandro Delgado Daza, Lawrence L. Livornese Jr
      Pages 3-39
    3. Sunil Thomas, Rima Dilbarova, Rino Rappuoli
      Pages 41-55
    4. Fred Zepp
      Pages 57-84
  3. Trends in Vaccinology

    1. Front Matter
      Pages 85-85
    2. Marcin Michalik, Bardya Djahanshiri, Jack C. Leo, Dirk Linke
      Pages 87-106
    3. Radwa Ewaisha, Karen S. Anderson
      Pages 131-152
  4. Vaccines for Human Viral Diseases

    1. Front Matter
      Pages 153-153
    2. Diego Fontana, Marina Etcheverrigaray, Ricardo Kratje, Claudio Prieto
      Pages 155-166
    3. Shin Murakami, Kaori Terasaki, Shinji Makino
      Pages 187-206
    4. Hoai J. Ly, Nandadeva Lokugamage, Tetsuro Ikegami
      Pages 207-220
    5. Gustaf Ahlén, Lars Frelin
      Pages 221-244
    6. Maria Malm, Kirsi Tamminen, Vesna Blazevic
      Pages 259-268
    7. Clifton McPherson, Richard Chubet, Kathy Holtz, Yoshikazu Honda-Okubo, Dale Barnard, Manon Cox et al.
      Pages 269-284
    8. Luis Martínez-Sobrido, Benson Yee Hin Cheng, Juan Carlos de la Torre
      Pages 313-351
  5. Vaccines for Human Bacterial Diseases

    1. Front Matter
      Pages 353-353
    2. Jaemi S. Chu, Daniel O. Villarreal, David B. Weiner
      Pages 355-361
    3. Jerzy Karczewski, Jean-Luc Bodmer, James C. Cook, Rachel F. Xoconostle, Debbie D. Nahas, Joseph G. Joyce et al.
      Pages 385-396
    4. Karuna P. Karunakaran, Hong Yu, Leonard J. Foster, Robert C. Brunham
      Pages 419-432
    5. Luke R. Green, Joseph Eiden, Li Hao, Tom Jones, John Perez, Lisa K. McNeil et al.
      Pages 445-469
    6. Christina M. Small, Waithaka Mwangi, Maria D. Esteve-Gassent
      Pages 471-486
    7. Valentina A. Feodorova, Lidiya V. Sayapina, Vladimir L. Motin
      Pages 487-498
  6. Vaccines for Human Fungal Diseases

    1. Front Matter
      Pages 535-535
    2. Keigo Ueno, Makoto Urai, Kayo Ohkouchi, Yoshitsugu Miyazaki, Yuki Kinjo
      Pages 537-549
    3. Chiung-Yu Hung, Karen L. Wozniak, Garry T. Cole
      Pages 551-566
  7. Vaccines for Human Parasitic Diseases

    1. Front Matter
      Pages 567-567
    2. Felix F. Loeffler, Johannes Pfeil, Kirsten Heiss
      Pages 569-582
    3. Sreenivas Gannavaram, Parna Bhattacharya, Ranadhir Dey, Nevien Ismail, Kumar Avishek, Poonam Salotra et al.
      Pages 623-638
  8. Vaccines for Prion Diseases

    1. Front Matter
      Pages 655-655
    2. Kristen Marciniuk, Ryan Taschuk, Scott Napper
      Pages 657-680
  9. Vaccines for Substance Abuse and Toxins

    1. Front Matter
      Pages 681-681
    2. Tamar Sabo, Chanoch Kronman, Ohad Mazor
      Pages 683-694
    3. Oscar B. Torres, Carl R. Alving, Gary R. Matyas
      Pages 695-710
  10. Vaccines for Allergy

    1. Front Matter
      Pages 711-711
    2. Hidenori Takagi, Fumio Takaiwa
      Pages 713-721

About this book


This text provides a practical guide providing step-by-step protocol to design and develop vaccines. Chapters detail protocols for developing novel vaccines against infectious bacteria, viruses, fungi, and parasites for humans and animals. Volume 1: Vaccines for Human Diseases has an introductory section on how vaccines impacted diseases, the immunological mechanism of vaccines, future challenges for vaccinologists, and current trends in vaccinology. The design of human vaccines for viral, bacterial, fungal, parasitic and prion diseases as well as vaccines for drug abuse, allergy, and tumor vaccines are also described in this volume. As a volume in the highly successful Methods in Molecular Biology series, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.


Authoritative and practical, Vaccine Design: Methods and Protocols, Volume 1: Vaccines

for Human Diseases aims to ensure successful results in the further study of this vital field.


developing novel vaccines antigenic proteins vaccines in silico recombinant antigenic proteins

Editors and affiliations

  • Sunil Thomas
    • 1
  1. 1.Lankenau Institute for Medical ResearchWynnewoodUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3385-3
  • Online ISBN 978-1-4939-3387-7
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site