Overview
- Updates readers on essential findings concerning the cell physiology, biochemistry, pathophysiology and pharmacology of epithelial ion transport
- Addresses both basic research and clinical aspects
- All chapters written by leading scientists and clinicians
- Includes supplementary material: sn.pub/extras
Part of the book series: Physiology in Health and Disease (PIHD)
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About this book
This book sheds new light on the physiology, molecular biology and pathophysiology of epithelial ion channels and transporters. It combines the basic cellular models and functions by means of a compelling clinical perspective, addressing aspects from the laboratory bench to the bedside. The individual chapters, written by leading scientists and clinicians, explore specific ion channels and transporters located in the epithelial tissues of the kidney, intestine, pancreas and respiratory tract, all of which play a crucial part in maintaining homeostasis. Further topics include the fundamentals of epithelial transport; mathematical modeling of ion transport; cell volume regulation; membrane protein folding and trafficking; transepithelial transport functions; and lastly, a discussion of transport proteins as potential pharmacological targets with a focus on the pharmacology of potassium channels.Â
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Keywords
Table of contents (29 chapters)
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Front Matter
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Basic Epithelial Ion Transport Principles and Function
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Front Matter
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Epithelial Ion Channels and Transporters
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Front Matter
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Editors and Affiliations
Bibliographic Information
Book Title: Ion Channels and Transporters of Epithelia in Health and Disease
Editors: Kirk L. Hamilton, Daniel C Devor
Series Title: Physiology in Health and Disease
DOI: https://doi.org/10.1007/978-1-4939-3366-2
Publisher: Springer New York, NY
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: American Physiological Society 2016
Hardcover ISBN: 978-1-4939-3364-8Published: 15 December 2015
eBook ISBN: 978-1-4939-3366-2Published: 14 December 2015
Series ISSN: 2625-252X
Series E-ISSN: 2625-2538
Edition Number: 1
Number of Pages: XIV, 1019
Number of Illustrations: 137 b/w illustrations, 44 illustrations in colour
Topics: Human Physiology, Cell Physiology, Medical Biochemistry, Urology, Receptors