Includes cutting-edge methods and protocols
Provides step-by-step detail essential for reproducible results
Contains key notes and implementation advice from the experts
Includes supplementary material: sn.pub/extras
Table of contents (19 protocols)
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A Road Map Toward Systems Medicine
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- Antoine H. C. van Kampen, Perry D. Moerland
Pages 17-41
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- Mansoor Saqi, Johann Pellet, Irina Roznovat, Alexander Mazein, Stéphane Ballereau, Bertrand De Meulder et al.
Pages 43-60
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- Peter D. Caie, David J. Harrison
Pages 61-72
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- Damjana Rozman, Jure Acimovic, Bernd Schmeck
Pages 73-86
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- Lars Kuepfer, Andreas Schuppert
Pages 87-104
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Opinions and Persepectives
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Front Matter
Pages 105-105
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- Bernd Schmeck, Wilhelm Bertrams, Xin Lai, Julio Vera
Pages 119-133
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- Martin Eberhardt, Xin Lai, Namrata Tomar, Shailendra Gupta, Bernd Schmeck, Alexander Steinkasserer et al.
Pages 135-179
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- Silvio Parodi, Giuseppe Riccardi, Nicoletta Castagnino, Lorenzo Tortolina, Massimo Maffei, Gabriele Zoppoli et al.
Pages 181-219
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- Marek Ostaszewski, Alexander Skupin, Rudi Balling
Pages 221-250
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Systems Medicine Projects and Case Studies
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Front Matter
Pages 251-251
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- Maike K. Aurich, Ines Thiele
Pages 253-281
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- Josep Roca, Isaac Cano, David Gomez-Cabrero, Jesper Tegnér
Pages 283-303
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- Raheleh Amirkhah, Ali Farazmand, Olaf Wolkenhauer, Ulf Schmitz
Pages 305-330
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- Pınar Pir, Nicolas Le Novère
Pages 331-350
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Tools and Methodologies
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Front Matter
Pages 351-351
About this book
This volume guides readers through the field of systems medicine by defining the terminology, and describing how established computational methods form bioinformatics and systems biology can be taken forward to an integrative systems medicine approach. Chapters provide an outlook on the role that systems medicine may or should play in various medical fields, and describe different facets of the systems medicine approach in action. Ultimately it introduces tools, resources and methodologies from bioinformatics and systems biology, and how to apply these in a systems medicine project. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, and discuss experimental and computational approaches, methods, and tools that should be considered for a successful systems medicine project. Systems Medicine aims to motivate and provide guidance for collaborations across disciplines to tackle today's challenges related to human health and well-being.
Keywords
- bioinformatic
- chronic pulmonary disease
- human metabolism
- immune-related diseases
- lung diseases
- neurology
- regenerative stem cell
- systems medicine
- wet lab experiments
- Systems Biology