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Clinical Applications of Mass Spectrometry in Biomolecular Analysis

Methods and Protocols

  • Uttam Garg

Part of the Methods in Molecular Biology book series (MIMB, volume 1378)

Table of contents

  1. Front Matter
    Pages i-xv
  2. Catherine P. Riley, Richard E. Mathieu Jr., Carmen Wiley
    Pages 87-97
  3. Hernando Escobar, Mark M. Kushnir, Alan L. Rockwood, A. Wayne Meikle
    Pages 199-210
  4. Dean C. Carlow, Ryan C. Schofield, Michelle Denburg
    Pages 321-329
  5. Back Matter
    Pages 331-333

About this book

Introduction

This volume provides stepwise instructions for the analysis of numerous clinically important analytes by mass spectrometry. Mass spectrometry offers clinical laboratory scientists a number of advantages including increased sensitivity and specificity, multiple component analysis, and no need for specialized reagents. The techniques described are a must for the measurement of many clinically relevant analytes in the fields of drug analysis, endocrinology, and inborn errors of metabolism. Each chapter provides a brief introduction about a specified analyte, followed by detailed instructions on the analytical protocol. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting edge and practical, Clinical Applications of Mass Spectrometry in Biomolecular Analysis: Methods and Protocols is a great resource for clinical laboratory scientists who are already using or thinking of bringing mass spectrometry to their laboratories.

Keywords

Estradiol Estrone High-Throughput Serum Insulin Liquid Chromatography Metanephrines Plasma Tandem Mass Spectrometry

Editors and affiliations

  • Uttam Garg
    • 1
  1. 1.Dept of Pathology & Lab MedicineChildren's Mercy Hospitals & ClinicsKansas CityUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-3182-8
  • Copyright Information Springer Science+Business Media New York 2016
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-3181-1
  • Online ISBN 978-1-4939-3182-8
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • Buy this book on publisher's site