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Patient-Specific Induced Pluripotent Stem Cell Models

Generation and Characterization

  • Book
  • © 2016

Overview

Editors:
  1. Andras Nagy

    1. Lunenfeld-Tanenbaum Research Institute, Toronto, Canada

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    You can also search for this editor in PubMed   Google Scholar

  2. Kursad Turksen

    1. Ottawa Hospital Research Institute, Ottawa, Canada

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge methods and protocols for studying patient-specific iPS cells
  • Provides step-by-step detail essential for reproducible results
  • Contains key notes and implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 1353)

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Table of contents (23 protocols)

  1. Modeling Axonal Phenotypes with Human Pluripotent Stem Cells

    • Kyle R. Denton, Chong-Chong Xu, Xue-Jun Li
    Pages 309-321

  2. Mitochondrial Disease-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization

    • Xuan Zhang, Shishi Li, Wei Yang, Huaye Pan, Dajiang Qin, Xufen Zhu et al.
    Pages 323-342

  3. Patient-Specific Induced Pluripotent Stem Cell Models: Characterization of iPS Cell-Derived Cardiomyocytes

    • Toru Egashira, Shinsuke Yuasa, Shugo Tohyama, Yusuke Kuroda, Tomoyuki Suzuki, Tomohisa Seki et al.
    Pages 343-353

  4. Generation of Integration-Free Patient Specific iPS Cells Using Episomal Plasmids Under Feeder Free Conditions

    • Sara Caxaria, Susanne Arthold, Amit C. Nathwani, Pollyanna Agnes Goh
    Pages 355-366

  5. Back Matter

    Pages 367-368
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Keywords

About this book

This volume captures the rapid developments in the field of induced pluripotent stem (iPS) cells, which have provided novel opportunities and approaches both for better understanding a number of human diseases and for developing new platforms for drug development and screening for such diseases. Specifically, representative protocols on various disease models have been collected from labs around the world. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization is an ideal reference for scientists working on furthering iPS research.

Editors and Affiliations

  • Lunenfeld-Tanenbaum Research Institute, Toronto, Canada

    Andras Nagy

  • Ottawa Hospital Research Institute, Ottawa, Canada

    Kursad Turksen

Bibliographic Information

  • Book Title: Patient-Specific Induced Pluripotent Stem Cell Models

  • Book Subtitle: Generation and Characterization

  • Editors: Andras Nagy, Kursad Turksen

  • Series Title: Methods in Molecular Biology

  • DOI: https://doi.org/10.1007/978-1-4939-3034-0

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: Springer Science+Business Media New York 2016

  • Hardcover ISBN: 978-1-4939-3033-3Published: 08 November 2015

  • Softcover ISBN: 978-1-4939-4973-1Published: 23 August 2016

  • eBook ISBN: 978-1-4939-3034-0Published: 07 November 2015

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: XIII, 368

  • Topics: Cell Biology

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