Diagnosis and Management of Pulmonary Hypertension

1. Front Matter

   Pages i-xiv

   PDF

2. The Pulmonary Circulation

   • Victor F. Tapson

   Pages 1-20

3. Epidemiology and Disease Classification of Pulmonary Hypertension

   • Rogerio Souza, Carlos Jardim, Marc Humbert

   Pages 21-35

4. Pathogenesis of Pulmonary Arterial Hypertension

   • Aaron W. Trammell, Anna R. Hemnes

   Pages 37-65

5. Hypoxic Pulmonary Hypertension

   • Kara Goss, Tim Lahm

   Pages 67-92

6. Pulmonary Hypertension in Chronic Heart and Lung Disease

   • Robert P. Frantz

   Pages 93-113

7. Chronic Thromboembolic Pulmonary Hypertension

   • William R. Auger, Peter F. Fedullo

   Pages 115-142

8. Schistosomiasis-Associated Pulmonary Arterial Hypertension

   • Rita de Cassia dos Santos Ferreira, Angela Pontes Bandeira, Ana Lúcia Coutinho Domingues

   Pages 143-163

9. Approach to the Patient with Elevated Pulmonary Arterial Pressure

   • Jason S. Fritz, Harold I. Palevsky

   Pages 165-201

10. Echocardiography

    • Paul Forfia

    Pages 203-224

11. Pulmonary Hemodynamics and Right Heart Catheterization

    • Saurabh Rajpal, Yonatan Buber, Michael J. Landzberg

    Pages 225-264

12. Cardiopulmonary Exercise Testing in Pulmonary Hypertension

    • David M. Systrom, Aaron B. Waxman

    Pages 265-301

13. Adjunct Therapy and Calcium Channel Blockers

    • Terence K. Trow

    Pages 303-321

14. Prostacyclin Therapy for Pulmonary Arterial Hypertension

    • Ioana R. Preston

    Pages 323-340

15. Endothelin Receptor Antagonists

    • Josanna Rodriguez-Lopez, Richard N. Channick

    Pages 341-354

16. Modulation of cGMP Synthesis and Metabolism

    • Kristen J. Bubb, Adrian J. Hobbs, James R. Klinger

    Pages 355-375

17. Combination Therapy for the Treatment of Pulmonary Arterial Hypertension

    • Andrew T. Levinson, James R. Klinger

    Pages 377-396

18. Investigative Therapies in Pulmonary Arterial Hypertension

    • Karen A. Fagan

    Pages 397-412

19. Pulmonary Hypertension in Critically Ill Patients

    • Hooman D. Poor, Corey E. Ventetuolo, Todd M. Bull

    Pages 413-436

20. Perioperative Management of Pulmonary Hypertension

    • Yuliya B. Goldsmith, Natalia Ivascu, Dana McGlothlin, Paul M. Heerdt, Evelyn M. Horn

    Pages 437-464

This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment. It discusses the definition and classification of these disorders and the epidemiology of pulmonary arterial hypertension (PAH); explores the approach to diagnosis and evaluation via methods such as echocardiography, right heart catheterization, and cardiopulmonary exercise testing; describes the major drug classes used to treat PAH and the cell signaling pathways that they target as well as adjunct and investigative therapies; and highlights special situations that are particularly challenging in the management of PAH. Written by experts in their respective fields, Diagnosis and Management of Pulmonary Hypertension is a valuable resource for pulmonologists, cardiologists, and practitioners in internal medicine and critical care.   

• Arterial
• Arterial Pressure
• Hypertension
• Pulmonary
• Therapeutic Approach
• Vascular Remodeling

• Division of Pulmonary, Sleep and Critical Care Medicine, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, USA

  James R. Klinger

• Department of Medicine, Mayo Clinic College of Medicine, Rochester, USA

  Robert P. Frantz

James R. Klinger, MD is a graduate of the Medical College of Wisconsin, Milwaukee, WI. He performed his residency at the Medical College of Pennsylvania, Philadelphia, PA and fellowship at Rhode Island Hospital and Brown University School of Medicine in pulmonary and critical care medicine. He is licensed and certified in internal medicine and critical care medicine. His teaching role includes being a lecturer in pulmonary pathophysiology as well as extensive hospital teaching roles at Rhode Island Hospital for house staff and pulmonary fellows. Klinger’s numerous publications can be viewed in Chest, the Journal of Applied Physiology, American Journal of Respiratory Critical Care Medicine, American Journal of Medicine, and many more. His research concerns development of therapies to treat pulmonary hypertension as well as research in the field of blood clotting, which can be one cause of pulmonary hypertension. Klinger is an active speaker and expert in the field of pulmonary hypertension and has many speaking engagements across the country.

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