Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer

1. Front Matter

   Pages i-xiii

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2. Epidemiology of Ductal Carcinoma In Situ

   • Prathima Kanumuri, Anees B. Chagpar

   Pages 1-11

3. Role of Screening Mammography in Early Detection/Outcome of Breast Cancer

   • Renee W. Pinsky, Mark A. Helvie

   Pages 13-26

4. Imaging DCIS: Digital/Film-Screening Mammography, Tomosynthesis, MRI, Ultrasonography

   • Annette Ingram Joe, Stephanie K. Patterson

   Pages 27-37

5. Pathology of Ductal Carcinoma In Situ: Features and Diagnostic Challenges

   • Julie M. Jorns, Celina G. Kleer

   Pages 39-49

6. Molecular Markers in DCIS

   • Theresa L. Schwartz, Chelsea Horwood

   Pages 51-55

7. History of Ductal Carcinoma In Situ Management Based Upon Data from Prospective, Randomized Clinical Trials

   • Lisa A. Newman, Jessica M. Bensenhaver

   Pages 57-65

8. Extent and Role of Margin Control for DCIS Managed by Breast-Conserving Surgery

   • Melissa Pilewskie, Monica Morrow

   Pages 67-83

9. Ductal Carcinoma In Situ Treated with Breast-Conserving Surgery Alone

   • Jessica M. Bensenhaver

   Pages 85-90

10. DCIS Managed with BCS: Whole-Breast XRT vs. Partial Breast XRT

    • Chirag Shah, Frank A. Vicini

    Pages 91-98

11. Anti-HER2/neu Therapy in DCIS

    • Amelia Tower, Ruta D. Rao, Kalliopi P. Siziopikou, Melody A. Cobleigh, Thomas B. Julian

    Pages 99-108

12. Role of Genetic Profiling and Recurrence Scores in Treatment Planning for DCIS

    • Julie A. Margenthaler, Amy E. Cyr

    Pages 109-115

13. DCIS and Sentinel Lymph Node Biopsy

    • Alfred J. Colfry III, Alastair M. Thompson, Henry Mark Kuerer

    Pages 117-124

14. Role of Postmastectomy Radiation for DCIS

    • Corey W. Speers, Reshma Jagsi

    Pages 125-137

15. Monitoring and Surveillance Following DCIS Treatment

    • Jennifer L. Zakhireh, E. Shelley Hwang

    Pages 139-146

16. DCIS and Hereditary Susceptibility for Breast Cancer

    • Patrick G. Pilie, Kara J. Milliron, Sofia D. Merajver

    Pages 147-154

17. Introduction, Evolution, and Application of the Van Nuys Prognostic Index in DCIS

    • Aeisha K. S. Rivers

    Pages 155-160

18. Disparities in DCIS Detection and Outcomes Related to Race/Ethnicity

    • Erin A. Strong, Azadeh Stark, Lisa A. Newman

    Pages 161-166

19. Back Matter

    Pages 167-168

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This volume reviews the  evolution of information regarding the epidemiology of DCIS and its modes of detection, as well  as treatment options as a function of both clinical trial data and ongoing investigational therapeutic prospects. Several of the challenging and clinically-relevant scenarios of DCIS that appear in daily practice is discussed, including the difficulties of distinguishing “true” DCIS from borderline patterns of other breast diseases and the therapeutic implications of differentiating these various diagnoses. Particular attention is paid to pathologic evaluation of DCIS, including histologic patterns and the importance of margin evaluation/margin control. The text also explores the data regarding DCIS in medical research in hereditary susceptibility for breast cancer and race/ethnicity-associated disparities in breast cancer.

Written by experts in the field, Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer is a comprehensive, state-of-the art review of the field, and serves as a valuable resource for clinicians, surgeons and researchers with an interest in breast cancer.

• DCIS
• SERM therapy
• breast tomosynthesis
• ultrasonography
• surgical oncology

“This is a slim but meaty monograph on ductal carcinoma in situ (DCIS) and microinvasive breast cancer. ... The book is appropriately illustrated with mammograms and pathology examples and is heavily referenced. ... This is really most appropriate for specialists (medical and surgical oncologists) and specialty trainees. ... Trainees in these specialties will find it an excellent, balanced review of particularly thorny issues.” (Carol Scott-Conner, Doody's Book Reviews, September, 2016)

• Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, USA

  Lisa A. Newman, Jessica M. Bensenhaver

Lisa A. Newman, MD, MPH, FACS
Professor of Surgery, Director, Breast Care Center, University of Michigan Health System, Comprehensive Cancer Center, Ann Arbor, MI, USA

Jessica M. Bensenhaver, MD
Assistant Professor of Surgery, University of Michigan Health System, Comprehensive Cancer Center, Ann Arbor, MI, USA