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Molecular Pathology of Nervous System Tumors

Biological Stratification and Targeted Therapies

  • Book
  • © 2015

Overview

Editors:
  1. Matthias A. Karajannis

    1. Associate Professor of Pediatrics and Otolaryngology, NYU Langone Medical Center, New York, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. David Zagzag

    1. Professor of Pathology and Neurosurgery, NYU Langone Medical Center, New York, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Each chapter written by a team of experts in their field
  • Classic histopathology is integrated with underlying oncogenic signaling pathways and disease mechanisms
  • A comprehensive guide to the rapidly evolving field

Part of the book series: Molecular Pathology Library (MPLB, volume 8)

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About this book

This book serves as a comprehensive guide to the rapidly evolving field of molecular neuropathology of nervous system tumors, as well as the underlying biology and emerging molecular targeted therapies. Special emphasis is given to already established and emerging molecular diagnostic tests in neuropathology, as well as molecular targeted therapies. The book is organized by clinico-pathologic disease entities, and each chapter is written by a team of experts in their field.

Molecular Pathology of Nervous System Tumors is of great value and utility for physicians and scientists involved with or interested in the up-to-date diagnosis and treatment of patients with brain tumors.

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xv
    Download chapter PDF

  2. Hereditary Predisposition to Primary CNS Tumors

    • Uri Tabori, Matthias A. Karajannis, John G. Pappas
    Pages 1-22

  3. Brain Tumor Stem Cells

    • N. Sumru Bayin, Aram S. Modrek, Dimitris G. Placantonakis
    Pages 23-34

  4. Molecular Pathology Techniques

    • Matija Snuderl
    Pages 35-44

  5. Low-Grade Gliomas

    • Fausto J. Rodriguez, Daniel C. Bowers
    Pages 45-66

  6. Ependymoma

    • Till Milde, Andrey Korshunov, Olaf Witt, Stefan M. Pfister, Hendrik Witt
    Pages 67-75

  7. Adult High-Grade (Diffuse) Glioma

    • Katharine McNeill, Kenneth Aldape, Howard A. Fine
    Pages 77-93

  8. Pediatric High-Grade Gliomas and DIPG

    • Oren J. Becher, Kelly L. Barton, Kyle G. Halvorson, Roger McLendon
    Pages 95-104

  9. Oligodendroglial Tumors

    • Stephen Yip, Jaishri Blakeley
    Pages 105-120

  10. Medulloblastoma and CNS Primitive Neuroectodermal Tumors

    • David T. W. Jones, Andrey Korshunov, Stefan M. Pfister, Michael D. Taylor, Paul A. Northcott
    Pages 121-142

  11. Subependymal Giant Cell Astrocytoma

    • David H. Harter, Howard L. Weiner, David Zagzag
    Pages 143-151

  12. Germ Cell Tumors

    • Girish Dhall, Ashley A. Ibrahim, Eyas M. Hattab
    Pages 153-162

  13. Choroid Plexus Tumors

    • Sriram Venneti, Martin Hasselblatt, Johannes E. Wolff, Alexander R. Judkins
    Pages 163-175

  14. Atypical Teratoid Rhabdoid Tumors

    • Sriram Venneti, Ganjam V. Kalpana, Alexander R. Judkins, Sharon L. Gardner
    Pages 177-189

  15. Hemangioblastoma

    • Jasmeet Chadha Singh, David Zagzag
    Pages 191-200

  16. Schwannomas

    • Matthias A. Karajannis, Anat Stemmer-Rachamimov
    Pages 201-211

  17. Malignant Peripheral Nerve Sheath Tumors

    • Brian Weiss, Amy Sheil, Nancy Ratner
    Pages 213-223

  18. Meningiomas

    • Christian Mawrin, Michel Kalamarides
    Pages 225-238

  19. Back Matter

    Pages 239-247
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Reviews

“This is an outstanding text/atlas and reference for CNS and PNS tumors, diagnostically. … I highly rcommend tis book for cancer doctors, pathologists, and neurosurgeons at all levels of training. … Photos, diagrams, tables and flow charts are included to helpfully illustrate the comprehensive approach to the histologic grading typologies.” (Joseph J. Grenier, Amazon.com, July, 2015)

Editors and Affiliations

  • Associate Professor of Pediatrics and Otolaryngology, NYU Langone Medical Center, New York, USA

    Matthias A. Karajannis

  • Professor of Pathology and Neurosurgery, NYU Langone Medical Center, New York, USA

    David Zagzag

Bibliographic Information

  • Book Title: Molecular Pathology of Nervous System Tumors

  • Book Subtitle: Biological Stratification and Targeted Therapies

  • Editors: Matthias A. Karajannis, David Zagzag

  • Series Title: Molecular Pathology Library

  • DOI: https://doi.org/10.1007/978-1-4939-1830-0

  • Publisher: Springer New York, NY

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Science+Business Media New York 2015

  • Hardcover ISBN: 978-1-4939-1829-4Published: 22 November 2014

  • Softcover ISBN: 978-1-4939-4743-0Published: 22 September 2016

  • eBook ISBN: 978-1-4939-1830-0Published: 21 November 2014

  • Series ISSN: 1935-987X

  • Series E-ISSN: 1935-9888

  • Edition Number: 1

  • Number of Pages: XV, 247

  • Number of Illustrations: 43 b/w illustrations, 78 illustrations in colour

  • Topics: Pathology, Oncology, Neurosurgery

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