Glycosaminoglycans

Chemistry and Biology

  • Kuberan Balagurunathan
  • Hiroshi Nakato
  • Umesh R. Desai

Part of the Methods in Molecular Biology book series (MIMB, volume 1229)

Table of contents

  1. Front Matter
    Pages i-xvi
  2. Structure

    1. Front Matter
      Pages 1-1
    2. Chien-Fu Liang, Heung Sik Hahm, Peter H. Seeberger
      Pages 3-10
    3. April Joice, Karthik Raman, Caitlin Mencio, Maritza V. Quintero, Spencer Brown, Thao Kim Nu Nguyen et al.
      Pages 11-19
    4. Karthik Raman, Balagurunathan Kuberan, Sailaja Arungundram
      Pages 31-36
    5. Xylophone V. Victor, Vy M. Tran, Balagurunathan Kuberan, Thao Kim Nu Nguyen
      Pages 43-48
    6. Rami A. Al-Horani, Rajesh Karuturi, Stephen Verespy III, Umesh R. Desai
      Pages 49-67
    7. Caitlin Mencio, Dinesh R. Garud, Balagurunathan Kuberan, Mamoru Koketsu
      Pages 69-78
    8. Md. Ferdous Anower-E-Khuda, Koji Kimata
      Pages 95-103
    9. Miroslaw Lech, Ishan Capila, Ganesh V. Kaundinya
      Pages 119-128
    10. Athanasia P. Asimakopoulou, Christina Malavaki, Nikolaos A. Afratis, Achilleas D. Theocharis, Fotini N. Lamari, Nikos K. Karamanos
      Pages 129-141
    11. Evgenia Karousou, Athanasia P. Asimakopoulou, Vassiliki Zafeiropoulou, Manuela Viola, Luca Monti, Antonio Rossi et al.
      Pages 143-159
    12. Consuelo N. Beecher, Cynthia K. Larive
      Pages 173-187
    13. Anders Dagälv, Anders Lundequist, Beata Filipek-Górniok, Tabea Dierker, Inger Eriksson, Lena Kjellén
      Pages 189-200
    14. Davide Vigetti, Evgenia Karousou, Manuela Viola, Alberto Passi
      Pages 201-208

About this book

Introduction

 Glycosaminoglycans: Chemistry and Biology emphasizes several areas of glycosaminoglycan research especially analysis and application of GAGs using a variety of approaches.  Chapters focus on chemical and enzymatic synthesis of GAGs for therapeutic purposes; biophysical and biochemical methods for studying GAG-protein interactions; molecular approaches for modulating and defining GAG biosynthesis; informatics approaches for deciphering GAG code; computational approaches for establishing specific and/or non-specific interactions and genetic and biochemical tools for manipulating/visualizing glycosaminoglycan expression and studying their functions in a variety of model organisms. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

 Authoritative and practical, Glycosaminoglycans: Chemistry and Biology serves as a valuable manual for cutting edge methodologies and practical tips to overcome any obstacles with experimentation pertaining to chemistry and biology of glycosaminoglycans.

Keywords

GAG-protein interactions Glycosaminoglycan biopolymers defining GAG biosynthesis enzymatic synthesis of GAGs genetic and biochemical tools manipulating expression model organisms visualizing glycosaminoglycan expression

Editors and affiliations

  • Kuberan Balagurunathan
    • 1
  • Hiroshi Nakato
    • 2
  • Umesh R. Desai
    • 3
  1. 1.Department of Medicinal ChemistryUniversity of UtahSalt Lake CityUSA
  2. 2.Department of Genetics, Cell Biology and DevelopmentThe University of MinnesotaMinneapolisUSA
  3. 3.Department of Medicinal ChemistryVirginia Commonwealth UniversityRichmondUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-1-4939-1714-3
  • Copyright Information Springer Science+Business Media New York 2015
  • Publisher Name Humana Press, New York, NY
  • eBook Packages Springer Protocols
  • Print ISBN 978-1-4939-1713-6
  • Online ISBN 978-1-4939-1714-3
  • Series Print ISSN 1064-3745
  • Series Online ISSN 1940-6029
  • About this book