Skip to main content
  • Book
  • © 2014

Microbial Endocrinology: The Microbiota-Gut-Brain Axis in Health and Disease

  • Provides readers with a full understanding of the capabilities of the microbiota to interface with the brain and form the microbiota-gut-brain axis and a detailed examination of the consequences of the microbiota-driven gut-to-brain communication for both health and disease

  • Represents the realization that any attempt to understand the ability of the microbiota to interface with the brain must attempt to address multiple disciplines

  • Chapters cut across disciplines of microbiology, endocrinology, neurophysiology, evolution, and disease

  • Includes supplementary material: sn.pub/extras

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 817)

Part of the book sub series: Microbial Endocrinology (MICENDO)

Buying options

eBook USD 219.00
Price excludes VAT (USA)
  • ISBN: 978-1-4939-0897-4
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 279.99
Price excludes VAT (USA)
Hardcover Book USD 279.99
Price excludes VAT (USA)

This is a preview of subscription content, access via your institution.

Table of contents (19 chapters)

  1. Front Matter

    Pages i-xviii
  2. Basic Concepts Underlying the Microbiota-Gut-Brain Axis

    1. Front Matter

      Pages 1-1
    2. The Enteric Nervous System and Gastrointestinal Innervation: Integrated Local and Central Control

      • John B. Furness, Brid P. Callaghan, Leni R. Rivera, Hyun-Jung Cho
      Pages 39-71
    3. Intestinal Barrier Function and the Brain-Gut Axis

      • Carmen Alonso, María Vicario, Marc Pigrau, Beatriz Lobo, Javier Santos
      Pages 73-113
    4. Vagal Pathways for Microbiome-Brain-Gut Axis Communication

      • Paul Forsythe, John Bienenstock, Wolfgang A. Kunze
      Pages 115-133
    5. The Brain-Gut Axis in Health and Disease

      • Yasser Al Omran, Qasim Aziz
      Pages 135-153
  3. Mechanistic Factors Influencing the Microbiota-Gut-Brain Axis

    1. Front Matter

      Pages 155-155
    2. Gastrointestinal Hormones and Their Targets

      • Jens F. Rehfeld
      Pages 157-175
    3. Neuropeptides and the Microbiota-Gut-Brain Axis

      • Peter Holzer, Aitak Farzi
      Pages 195-219
    4. Bacterial Neuroactive Compounds Produced by Psychobiotics

      • Rebecca Wall, John F. Cryan, R. Paul Ross, Gerald F. Fitzgerald, Timothy G. Dinan, Catherine Stanton
      Pages 221-239
  4. The Microbiota-Gut-Brain Axis in Health and Disease

    1. Front Matter

      Pages 277-277
    2. Microbiota, Inflammation and Obesity

      • Yolanda Sanz, Angela Moya-Pérez
      Pages 291-317
    3. Microbiota, Immunoregulatory Old Friends and Psychiatric Disorders

      • Graham A. W. Rook, Charles L. Raison, Christopher A. Lowry
      Pages 319-356
    4. Microbiota-Gut-Brain Axis and Cognitive Function

      • Mélanie G. Gareau
      Pages 357-371

About this book

The field of microbial endocrinology is expressly devoted to understanding the mechanisms by which the microbiota (bacteria within the microbiome) interact with the host (“us”). This interaction is a two-way street and the driving force that governs these interactions are the neuroendocrine products of both the host and the microbiota. Chapters include neuroendocrine hormone-induced changes in gene expression and microbial endocrinology and probiotics. This is the first in a series of books dedicated to understanding how bi-directional communication between host and bacteria represents the cutting edge of translational medical research, and hopefully identifies new ways to understand the mechanisms that determine health and disease.​

Keywords

  • disease
  • microbial endocrinology
  • microbiome
  • physiology

Editors and Affiliations

  • Immunotherapeutics and Biotechnology, Texas Tech University Health Sciences Center, Abilene, USA

    Mark Lyte

  • Department of Anatomy and Neuroscience, University College, Cork, Ireland

    John F. Cryan

Bibliographic Information

Buying options

eBook USD 219.00
Price excludes VAT (USA)
  • ISBN: 978-1-4939-0897-4
  • Instant PDF download
  • Readable on all devices
  • Own it forever
  • Exclusive offer for individuals only
  • Tax calculation will be finalised during checkout
Softcover Book USD 279.99
Price excludes VAT (USA)
Hardcover Book USD 279.99
Price excludes VAT (USA)